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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
| Target ID |
GM-T73725
|
| Target Name |
CLK2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1196
|
| Gene ID |
100063546 (Equus caballus), 101088998 (Felis catus), 1196 (Homo sapiens), 12748 (Mus musculus) 365842 (Rattus norvegicus), 490427 (Canis lupus familiaris), 512737 (Bos taurus), 717671 (Macaca mulatta)
|
| Target Alternative Names |
CDC-like kinase 2,CLK2,Clk2,Dual specificity protein kinase CLK2
|
| Uniprot Accession |
P49760,O35491
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSG00000176444, ENSMUSG00000068917, ENSCAFG00845012282, ENSBTAG00000014393, ENSMMUG00000023141
|
| Target Classification |
Kinase
|
Pre-made viral vector of CLK2 cDNA Clones/ORF Plasmid
CLK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1196 | Pre-made Human CLK2 siRNA oligo Duplex | 1196 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365842 | Pre-made Rat Clk2 siRNA oligo Duplex | 365842 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12748 | Pre-made Mouse Clk2 siRNA oligo Duplex | 12748 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717671 | Pre-made Cynomolgus/Rhesus macaque CLK2 siRNA oligo Duplex | 717671 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088998 | Pre-made Cat/Feline CLK2 siRNA oligo Duplex | 101088998 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490427 | Pre-made Dog/Canine CLK2 siRNA oligo Duplex | 490427 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512737 | Pre-made Bovines/Cattle CLK2 siRNA oligo Duplex | 512737 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063546 | Pre-made Equine/Horse CLK2 siRNA oligo Duplex | 100063546 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73725-Ab | Human | Anti-Human CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73725-Ab | Rat | Anti-Rat CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73725-Ab | Mouse | Anti-Mouse CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73725-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73725-Ab | Cat/Feline | Anti-Cat/Feline CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73725-Ab | Dog/Canine | Anti-Dog/Canine CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73725-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73725-Ab | Equine/Horse | Anti-Equine/Horse CLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CLK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73725-Ag | Human | Human CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T73725-Ag | Rat | Rat CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T73725-Ag | Mouse | Mouse CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T73725-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T73725-Ag | Cat/Feline | Cat/Feline CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T73725-Ag | Dog/Canine | Dog/Canine CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T73725-Ag | Bovines/Cattle | Bovines/Cattle CLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T73725-Ag | Equine/Horse | Equine/Horse CLK2 recombinant protein | Mammalian cell | Detail |