Recombinant multi-species NGAL/LCN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NGAL/LCN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
The Alternative Names of target: 24p3,25 kDa alpha-2-microglobulin-related subunit of MMP-9,LCN2,Lcn2,Lipocalin-2,MSFI,NGAL,NRL,Neutrophil gelatinase-associated lipocalin,Oncogene 24p3,Siderocalin,Sip24,p25

Target products collectionGo to NGAL/LCN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T72010-Ag-1/ GM-Tg-hg-T72010-Ag-2 Human NGAL/LCN2 protein Human
GM-Tg-rg-T72010-Ag-1/ GM-Tg-rg-T72010-Ag-2 Rat NGAL/LCN2 protein Rat
GM-Tg-mg-T72010-Ag-1/ GM-Tg-mg-T72010-Ag-2 Mouse NGAL/LCN2 protein Mouse
GM-Tg-cynog-T72010-Ag-1/ GM-Tg-cynog-T72010-Ag-2 Cynomolgus/Rhesus macaque NGAL/LCN2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T72010-Ag-1/ GM-Tg-felg-T72010-Ag-2 Feline NGAL/LCN2 protein Feline
GM-Tg-cang-T72010-Ag-1/ GM-Tg-cang-T72010-Ag-2 Canine NGAL/LCN2 protein Canine
GM-Tg-bovg-T72010-Ag-1/ GM-Tg-bovg-T72010-Ag-2 Bovine NGAL/LCN2 protein Bovine
GM-Tg-equg-T72010-Ag-1/ GM-Tg-equg-T72010-Ag-2 Equine NGAL/LCN2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T72010-Ag-1/ GM-Tg-hg-T72010-Ag-2; GM-Tg-rg-T72010-Ag-1/ GM-Tg-rg-T72010-Ag-2;
GM-Tg-mg-T72010-Ag-1/ GM-Tg-mg-T72010-Ag-2; GM-Tg-cynog-T72010-Ag-1/ GM-Tg-cynog-T72010-Ag-2;
GM-Tg-felg-T72010-Ag-1/ GM-Tg-felg-T72010-Ag-2; GM-Tg-cang-T72010-Ag-1/ GM-Tg-cang-T72010-Ag-2;
GM-Tg-bovg-T72010-Ag-1/ GM-Tg-bovg-T72010-Ag-2; GM-Tg-equg-T72010-Ag-1/ GM-Tg-equg-T72010-Ag-2
Products Name NGAL/LCN2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NGAL/LCN2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NGAL/LCN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.