Recombinant multi-species GSK3B/GSK-3B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSK3B/GSK-3B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
The Alternative Names of target: 7330414F15Rik,8430431H08Rik,GSK-3,GSK-3 beta,GSK-3B,GSK-3beta,GSK3,GSK3B,GSK3beta,Glycogen synthase kinase-3 beta,Gsk3b,Serine/threonine-protein kinase GSK3B

Target products collectionGo to GSK3B/GSK-3B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T70977-Ag-1/ GM-Tg-hg-T70977-Ag-2 Human GSK3B/GSK-3B protein Human
GM-Tg-rg-T70977-Ag-1/ GM-Tg-rg-T70977-Ag-2 Rat GSK3B/GSK-3B protein Rat
GM-Tg-mg-T70977-Ag-1/ GM-Tg-mg-T70977-Ag-2 Mouse GSK3B/GSK-3B protein Mouse
GM-Tg-cynog-T70977-Ag-1/ GM-Tg-cynog-T70977-Ag-2 Cynomolgus/Rhesus macaque GSK3B/GSK-3B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T70977-Ag-1/ GM-Tg-felg-T70977-Ag-2 Feline GSK3B/GSK-3B protein Feline
GM-Tg-cang-T70977-Ag-1/ GM-Tg-cang-T70977-Ag-2 Canine GSK3B/GSK-3B protein Canine
GM-Tg-bovg-T70977-Ag-1/ GM-Tg-bovg-T70977-Ag-2 Bovine GSK3B/GSK-3B protein Bovine
GM-Tg-equg-T70977-Ag-1/ GM-Tg-equg-T70977-Ag-2 Equine GSK3B/GSK-3B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T70977-Ag-1/ GM-Tg-hg-T70977-Ag-2; GM-Tg-rg-T70977-Ag-1/ GM-Tg-rg-T70977-Ag-2;
GM-Tg-mg-T70977-Ag-1/ GM-Tg-mg-T70977-Ag-2; GM-Tg-cynog-T70977-Ag-1/ GM-Tg-cynog-T70977-Ag-2;
GM-Tg-felg-T70977-Ag-1/ GM-Tg-felg-T70977-Ag-2; GM-Tg-cang-T70977-Ag-1/ GM-Tg-cang-T70977-Ag-2;
GM-Tg-bovg-T70977-Ag-1/ GM-Tg-bovg-T70977-Ag-2; GM-Tg-equg-T70977-Ag-1/ GM-Tg-equg-T70977-Ag-2
Products Name GSK3B/GSK-3B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GSK3B/GSK-3B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSK3B/GSK-3B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.