Recombinant multi-species GADD45B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD45B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway.  This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
The Alternative Names of target: GADD45B,GADD45BETA,Gadd45b,Growth arrest and DNA damage-inducible protein GADD45 beta,MYD118,Myd118,Myeloid differentiation primary response protein MyD118,Negative growth regulatory protein MyD118

Target products collectionGo to GADD45B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T70797-Ag-1/ GM-Tg-hg-T70797-Ag-2 Human GADD45B protein Human
GM-Tg-rg-T70797-Ag-1/ GM-Tg-rg-T70797-Ag-2 Rat GADD45B protein Rat
GM-Tg-mg-T70797-Ag-1/ GM-Tg-mg-T70797-Ag-2 Mouse GADD45B protein Mouse
GM-Tg-cynog-T70797-Ag-1/ GM-Tg-cynog-T70797-Ag-2 Cynomolgus/Rhesus macaque GADD45B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T70797-Ag-1/ GM-Tg-felg-T70797-Ag-2 Feline GADD45B protein Feline
GM-Tg-cang-T70797-Ag-1/ GM-Tg-cang-T70797-Ag-2 Canine GADD45B protein Canine
GM-Tg-bovg-T70797-Ag-1/ GM-Tg-bovg-T70797-Ag-2 Bovine GADD45B protein Bovine
GM-Tg-equg-T70797-Ag-1/ GM-Tg-equg-T70797-Ag-2 Equine GADD45B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T70797-Ag-1/ GM-Tg-hg-T70797-Ag-2; GM-Tg-rg-T70797-Ag-1/ GM-Tg-rg-T70797-Ag-2;
GM-Tg-mg-T70797-Ag-1/ GM-Tg-mg-T70797-Ag-2; GM-Tg-cynog-T70797-Ag-1/ GM-Tg-cynog-T70797-Ag-2;
GM-Tg-felg-T70797-Ag-1/ GM-Tg-felg-T70797-Ag-2; GM-Tg-cang-T70797-Ag-1/ GM-Tg-cang-T70797-Ag-2;
GM-Tg-bovg-T70797-Ag-1/ GM-Tg-bovg-T70797-Ag-2; GM-Tg-equg-T70797-Ag-1/ GM-Tg-equg-T70797-Ag-2
Products Name GADD45B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GADD45B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GADD45B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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