Explore GADD45B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T70797
|
| Target Name |
GADD45B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4616
|
| Gene ID |
100059768 (Equus caballus), 101087971 (Felis catus), 17873 (Mus musculus), 299626 (Rattus norvegicus)
4616 (Homo sapiens), 485069 (Canis lupus familiaris), 618405 (Bos taurus), 711257 (Macaca mulatta)
|
| Target Alternative Names |
GADD45B,GADD45BETA,Gadd45b,Growth arrest and DNA damage-inducible protein GADD45 beta,MYD118,Myd118,Myeloid differentiation primary response protein MyD118,Negative growth regulatory protein MyD118
|
| Uniprot Accession |
P22339,O75293,Q5E9A5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
MAPK signaling pathway, NF-kappa B signaling pathway, FoxO signaling pathway, p53 signaling pathway, Apoptosis, Cellular senescence, Epstein-Barr virus infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Thyroid cancer, Basal cell carcinoma, Melanoma, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSMUSG00000015312, ENSG00000099860, ENSCAFG00845011680, ENSBTAG00000025462, ENSMMUG00000003468
|
Pre-made viral vector of GADD45B cDNA Clones/ORF Plasmid
GADD45B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4616 | Pre-made Human GADD45B/MYD118/GADD45BETA siRNA oligo Duplex | 4616 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo299626 | Pre-made Rat Gadd45b siRNA oligo Duplex | 299626 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17873 | Pre-made Mouse Gadd45b/Myd118 siRNA oligo Duplex | 17873 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711257 | Pre-made Cynomolgus/Rhesus macaque GADD45B siRNA oligo Duplex | 711257 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087971 | Pre-made Cat/Feline GADD45B siRNA oligo Duplex | 101087971 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485069 | Pre-made Dog/Canine GADD45B siRNA oligo Duplex | 485069 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo618405 | Pre-made Bovines/Cattle GADD45B siRNA oligo Duplex | 618405 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059768 | Pre-made Equine/Horse GADD45B siRNA oligo Duplex | 100059768 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GADD45B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T70797-Ab | Human | Anti-Human GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T70797-Ab | Rat | Anti-Rat GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T70797-Ab | Mouse | Anti-Mouse GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T70797-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T70797-Ab | Cat/Feline | Anti-Cat/Feline GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T70797-Ab | Dog/Canine | Anti-Dog/Canine GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T70797-Ab | Bovines/Cattle | Anti-Bovines/Cattle GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T70797-Ab | Equine/Horse | Anti-Equine/Horse GADD45B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GADD45B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T70797-Ag | Human | Human GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T70797-Ag | Rat | Rat GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T70797-Ag | Mouse | Mouse GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T70797-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T70797-Ag | Cat/Feline | Cat/Feline GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T70797-Ag | Dog/Canine | Dog/Canine GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T70797-Ag | Bovines/Cattle | Bovines/Cattle GADD45B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T70797-Ag | Equine/Horse | Equine/Horse GADD45B recombinant protein | Mammalian cell | Detail |
