Recombinant multi-species Cathepsin C/CTSC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin C/CTSC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]
The Alternative Names of target: CATC,CPPI,CTSC,CatC,Cathepsin C,Cathepsin J,Ctsc,DPP-I,DPP1,DPPI,DPPI),Dipeptidyl peptidase 1,Dipeptidyl peptidase I (DPP-I,Dipeptidyl transferase,HMS,JP,JPD,PALS,PDON1,PLS

Target products collectionGo to Cathepsin C/CTSC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T70490-Ag-1/ GM-Tg-hg-T70490-Ag-2 Human Cathepsin C/CTSC protein Human
GM-Tg-rg-T70490-Ag-1/ GM-Tg-rg-T70490-Ag-2 Rat Cathepsin C/CTSC protein Rat
GM-Tg-mg-T70490-Ag-1/ GM-Tg-mg-T70490-Ag-2 Mouse Cathepsin C/CTSC protein Mouse
GM-Tg-cynog-T70490-Ag-1/ GM-Tg-cynog-T70490-Ag-2 Cynomolgus/Rhesus macaque Cathepsin C/CTSC protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T70490-Ag-1/ GM-Tg-felg-T70490-Ag-2 Feline Cathepsin C/CTSC protein Feline
GM-Tg-cang-T70490-Ag-1/ GM-Tg-cang-T70490-Ag-2 Canine Cathepsin C/CTSC protein Canine
GM-Tg-bovg-T70490-Ag-1/ GM-Tg-bovg-T70490-Ag-2 Bovine Cathepsin C/CTSC protein Bovine
GM-Tg-equg-T70490-Ag-1/ GM-Tg-equg-T70490-Ag-2 Equine Cathepsin C/CTSC protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T70490-Ag-1/ GM-Tg-hg-T70490-Ag-2; GM-Tg-rg-T70490-Ag-1/ GM-Tg-rg-T70490-Ag-2;
GM-Tg-mg-T70490-Ag-1/ GM-Tg-mg-T70490-Ag-2; GM-Tg-cynog-T70490-Ag-1/ GM-Tg-cynog-T70490-Ag-2;
GM-Tg-felg-T70490-Ag-1/ GM-Tg-felg-T70490-Ag-2; GM-Tg-cang-T70490-Ag-1/ GM-Tg-cang-T70490-Ag-2;
GM-Tg-bovg-T70490-Ag-1/ GM-Tg-bovg-T70490-Ag-2; GM-Tg-equg-T70490-Ag-1/ GM-Tg-equg-T70490-Ag-2
Products Name Cathepsin C/CTSC protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cathepsin C/CTSC
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin C/CTSC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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