Cathepsin C/CTSC Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Cathepsin C/CTSC gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]

Target ID GM-T70490
Target Name Cathepsin C/CTSC
Gene Group ldentifer
(Target Gene ID in Homo species)
1075
Gene ID 100060401 (Equus caballus), 101092140 (Felis catus), 1075 (Homo sapiens), 13032 (Mus musculus)
25423 (Rattus norvegicus), 352958 (Bos taurus), 403458 (Canis lupus familiaris), 705320 (Macaca mulatta)
Target Alternative Names CATC,CPPI,CTSC,CatC,Cathepsin C,Cathepsin J,Ctsc,DPP-I,DPP1,DPPI,DPPI),Dipeptidyl peptidase 1,Dipeptidyl peptidase I (DPP-I,Dipeptidyl transferase,HMS,JP,JPD,PALS,PDON1,PLS
Uniprot Accession P53634,P97821,P80067,Q3ZCJ8,O97578
Protein Sub-location Secreted Protein/Potential Cytokines
Category Therapeutics Target
Disease from KEGG Lysosome, Apoptosis
Gene Ensembl ENSECAG00000020881, ENSG00000109861, ENSMUSG00000030560, ENSBTAG00000011100, ENSCAFG00845026305, ENSMMUG00000022139


Pre-made viral vector of Cathepsin C/CTSC cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001862Human CTSC/CPPI/DPP-I Lentivirus plasmidNM_0011141731075HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001862Human CTSC/CPPI/DPP-I Lentivirus particleNM_0011141731075HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm001734Mouse Ctsc/AI047818/CatC Lentivirus plasmidNM_00998213032MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001773Mouse Ctsc/CatC/DPP1 Mammalian (Non-Viral Vector) plasmidNM_009982.613032MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLPm001734Mouse Ctsc/AI047818/CatC Lentivirus particleNM_00998213032MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Cathepsin C/CTSC siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo1075Pre-made Human CTSC/JP/HMS siRNA oligo Duplex1075HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25423Pre-made Rat Ctsc/CATC/DPPI siRNA oligo Duplex25423RatIn-vitro grade; in-vivo gradeDetail
pGMoligo13032Pre-made Mouse Ctsc/CatC/DPP1 siRNA oligo Duplex13032MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo705320Pre-made Cynomolgus/Rhesus macaque CTSC siRNA oligo Duplex705320Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092140Pre-made Cat/Feline CTSC siRNA oligo Duplex101092140Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403458Pre-made Dog/Canine CTSC/DPPI/DPP-I siRNA oligo Duplex403458Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo352958Pre-made Bovines/Cattle CTSC siRNA oligo Duplex352958Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100060401Pre-made Equine/Horse CTSC siRNA oligo Duplex100060401Equine/HorseIn-vitro grade; in-vivo gradeDetail


Cathepsin C/CTSC antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T70490-AbHumanAnti-Human Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T70490-AbRatAnti-Rat Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T70490-AbMouseAnti-Mouse Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T70490-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T70490-AbCat/FelineAnti-Cat/Feline Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T70490-AbDog/CanineAnti-Dog/Canine Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T70490-AbBovines/CattleAnti-Bovines/Cattle Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T70490-AbEquine/HorseAnti-Equine/Horse Cathepsin C/CTSC monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Cathepsin C/CTSC recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T70490-AgHumanHuman Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-rg-T70490-AgRatRat Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-mg-T70490-AgMouseMouse Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-cynog-T70490-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-felg-T70490-AgCat/FelineCat/Feline Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-cang-T70490-AgDog/CanineDog/Canine Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-bovg-T70490-AgBovines/CattleBovines/Cattle Cathepsin C/CTSC recombinant proteinMammalian cellDetail
GM-Tg-equg-T70490-AgEquine/HorseEquine/Horse Cathepsin C/CTSC recombinant proteinMammalian cellDetail