Recombinant multi-species CDK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
The Alternative Names of target: A630093N05Rik,CDK2,CDKN2,Cdk2,Cell division protein kinase 2,Cyclin-dependent kinase 2,p33 protein kinase,p33(CDK2)

Target products collectionGo to CDK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T70176-Ag-1/ GM-Tg-hg-T70176-Ag-2 Human CDK2 protein Human
GM-Tg-rg-T70176-Ag-1/ GM-Tg-rg-T70176-Ag-2 Rat CDK2 protein Rat
GM-Tg-mg-T70176-Ag-1/ GM-Tg-mg-T70176-Ag-2 Mouse CDK2 protein Mouse
GM-Tg-cynog-T70176-Ag-1/ GM-Tg-cynog-T70176-Ag-2 Cynomolgus/Rhesus macaque CDK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T70176-Ag-1/ GM-Tg-felg-T70176-Ag-2 Feline CDK2 protein Feline
GM-Tg-cang-T70176-Ag-1/ GM-Tg-cang-T70176-Ag-2 Canine CDK2 protein Canine
GM-Tg-bovg-T70176-Ag-1/ GM-Tg-bovg-T70176-Ag-2 Bovine CDK2 protein Bovine
GM-Tg-equg-T70176-Ag-1/ GM-Tg-equg-T70176-Ag-2 Equine CDK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T70176-Ag-1/ GM-Tg-hg-T70176-Ag-2; GM-Tg-rg-T70176-Ag-1/ GM-Tg-rg-T70176-Ag-2;
GM-Tg-mg-T70176-Ag-1/ GM-Tg-mg-T70176-Ag-2; GM-Tg-cynog-T70176-Ag-1/ GM-Tg-cynog-T70176-Ag-2;
GM-Tg-felg-T70176-Ag-1/ GM-Tg-felg-T70176-Ag-2; GM-Tg-cang-T70176-Ag-1/ GM-Tg-cang-T70176-Ag-2;
GM-Tg-bovg-T70176-Ag-1/ GM-Tg-bovg-T70176-Ag-2; GM-Tg-equg-T70176-Ag-1/ GM-Tg-equg-T70176-Ag-2
Products Name CDK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.