Explore CDK2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
| Target ID |
GM-T70176
|
| Target Name |
CDK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1017
|
| Gene ID |
100051790 (Equus caballus), 100855704 (Canis lupus familiaris), 101093368 (Felis catus), 1017 (Homo sapiens)
12566 (Mus musculus), 362817 (Rattus norvegicus), 519217 (Bos taurus), 711002 (Macaca mulatta)
|
| Target Alternative Names |
A630093N05Rik,CDK2,CDKN2,Cdk2,Cell division protein kinase 2,Cyclin-dependent kinase 2,p33 protein kinase,p33(CDK2)
|
| Uniprot Accession |
P24941,P97377,Q63699,Q5E9Y0
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
FoxO signaling pathway, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syndrome, Hepatitis C, Hepatitis B, Measles, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Prostate cancer, Small cell lung cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000021177, ENSCAFG00845005902, ENSG00000123374, ENSMUSG00000025358, ENSBTAG00000004021, ENSMMUG00000018814
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CDK2 cDNA Clones/ORF Plasmid
CDK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1017 | Pre-made Human CDK2/CDKN2/p33(CDK2) siRNA oligo Duplex | 1017 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362817 | Pre-made Rat Cdk2 siRNA oligo Duplex | 362817 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12566 | Pre-made Mouse Cdk2/A630093N05Rik siRNA oligo Duplex | 12566 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711002 | Pre-made Cynomolgus/Rhesus macaque CDK2 siRNA oligo Duplex | 711002 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093368 | Pre-made Cat/Feline CDK2 siRNA oligo Duplex | 101093368 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855704 | Pre-made Dog/Canine CDK2 siRNA oligo Duplex | 100855704 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519217 | Pre-made Bovines/Cattle CDK2 siRNA oligo Duplex | 519217 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051790 | Pre-made Equine/Horse CDK2 siRNA oligo Duplex | 100051790 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CDK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T70176-Ab | Human | Anti-Human CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T70176-Ab | Rat | Anti-Rat CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T70176-Ab | Mouse | Anti-Mouse CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T70176-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T70176-Ab | Cat/Feline | Anti-Cat/Feline CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T70176-Ab | Dog/Canine | Anti-Dog/Canine CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T70176-Ab | Bovines/Cattle | Anti-Bovines/Cattle CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T70176-Ab | Equine/Horse | Anti-Equine/Horse CDK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CDK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T70176-Ag | Human | Human CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T70176-Ag | Rat | Rat CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T70176-Ag | Mouse | Mouse CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T70176-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T70176-Ag | Cat/Feline | Cat/Feline CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T70176-Ag | Dog/Canine | Dog/Canine CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T70176-Ag | Bovines/Cattle | Bovines/Cattle CDK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T70176-Ag | Equine/Horse | Equine/Horse CDK2 recombinant protein | Mammalian cell | Detail |
