Recombinant multi-species FGF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AIGF,Aigf,Androgen-induced growth factor (AIGF),FGF-8,FGF6C,FGF8,Fgf-8,Fgf6c,Fgf8,Fibroblast growth factor 8,HBGF-8,HH6,Heparin-binding growth factor 8 (HBGF-8),KAL6

Target products collectionGo to FGF8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T69580-Ag-1/ GM-Tg-hg-T69580-Ag-2 Human FGF8 protein Human
GM-Tg-rg-T69580-Ag-1/ GM-Tg-rg-T69580-Ag-2 Rat FGF8 protein Rat
GM-Tg-mg-T69580-Ag-1/ GM-Tg-mg-T69580-Ag-2 Mouse FGF8 protein Mouse
GM-Tg-cynog-T69580-Ag-1/ GM-Tg-cynog-T69580-Ag-2 Cynomolgus/Rhesus macaque FGF8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T69580-Ag-1/ GM-Tg-felg-T69580-Ag-2 Feline FGF8 protein Feline
GM-Tg-cang-T69580-Ag-1/ GM-Tg-cang-T69580-Ag-2 Canine FGF8 protein Canine
GM-Tg-bovg-T69580-Ag-1/ GM-Tg-bovg-T69580-Ag-2 Bovine FGF8 protein Bovine
GM-Tg-equg-T69580-Ag-1/ GM-Tg-equg-T69580-Ag-2 Equine FGF8 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T69580-Ag-1/ GM-Tg-hg-T69580-Ag-2; GM-Tg-rg-T69580-Ag-1/ GM-Tg-rg-T69580-Ag-2;
GM-Tg-mg-T69580-Ag-1/ GM-Tg-mg-T69580-Ag-2; GM-Tg-cynog-T69580-Ag-1/ GM-Tg-cynog-T69580-Ag-2;
GM-Tg-felg-T69580-Ag-1/ GM-Tg-felg-T69580-Ag-2; GM-Tg-cang-T69580-Ag-1/ GM-Tg-cang-T69580-Ag-2;
GM-Tg-bovg-T69580-Ag-1/ GM-Tg-bovg-T69580-Ag-2; GM-Tg-equg-T69580-Ag-1/ GM-Tg-equg-T69580-Ag-2
Products Name FGF8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FGF8
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.