Recombinant multi-species HDAC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
The Alternative Names of target: GON-10,HD1,HDAC1,Hdac1,Hdac1-ps,Histone deacetylase 1,KDAC1,MommeD5,Protein deacetylase HDAC1,Protein deacylase HDAC1,RPD3,RPD3L1

Target products collectionGo to HDAC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T68547-Ag-1/ GM-Tg-hg-T68547-Ag-2 Human HDAC1 protein Human
GM-Tg-rg-T68547-Ag-1/ GM-Tg-rg-T68547-Ag-2 Rat HDAC1 protein Rat
GM-Tg-mg-T68547-Ag-1/ GM-Tg-mg-T68547-Ag-2 Mouse HDAC1 protein Mouse
GM-Tg-cynog-T68547-Ag-1/ GM-Tg-cynog-T68547-Ag-2 Cynomolgus/Rhesus macaque HDAC1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T68547-Ag-1/ GM-Tg-felg-T68547-Ag-2 Feline HDAC1 protein Feline
GM-Tg-cang-T68547-Ag-1/ GM-Tg-cang-T68547-Ag-2 Canine HDAC1 protein Canine
GM-Tg-bovg-T68547-Ag-1/ GM-Tg-bovg-T68547-Ag-2 Bovine HDAC1 protein Bovine
GM-Tg-equg-T68547-Ag-1/ GM-Tg-equg-T68547-Ag-2 Equine HDAC1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T68547-Ag-1/ GM-Tg-hg-T68547-Ag-2; GM-Tg-rg-T68547-Ag-1/ GM-Tg-rg-T68547-Ag-2;
GM-Tg-mg-T68547-Ag-1/ GM-Tg-mg-T68547-Ag-2; GM-Tg-cynog-T68547-Ag-1/ GM-Tg-cynog-T68547-Ag-2;
GM-Tg-felg-T68547-Ag-1/ GM-Tg-felg-T68547-Ag-2; GM-Tg-cang-T68547-Ag-1/ GM-Tg-cang-T68547-Ag-2;
GM-Tg-bovg-T68547-Ag-1/ GM-Tg-bovg-T68547-Ag-2; GM-Tg-equg-T68547-Ag-1/ GM-Tg-equg-T68547-Ag-2
Products Name HDAC1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HDAC1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.