Explore HDAC1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T68547
|
| Target Name |
HDAC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3065
|
| Gene ID |
100070281 (Equus caballus), 101099228 (Felis catus), 297893 (Rattus norvegicus), 3065 (Homo sapiens)
404126 (Bos taurus), 433759 (Mus musculus), 487309 (Canis lupus familiaris), 708441 (Macaca mulatta)
|
| Target Alternative Names |
GON-10,HD1,HDAC1,Hdac1,Hdac1-ps,Histone deacetylase 1,KDAC1,MommeD5,Protein deacetylase HDAC1,Protein deacylase HDAC1,RPD3,RPD3L1
|
| Uniprot Accession |
Q4QQW4,Q13547,Q32PJ8,O09106
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Longevity regulating pathway - multiple species, Thyroid hormone signaling pathway, Amphetamine addiction, Human papillomavirus infection, Epstein-Barr virus infection, Pathways in cancer, Chronic myeloid leukemia
|
| Gene Ensembl |
ENSECAG00000016082, ENSG00000116478, ENSBTAG00000012698, ENSMUSG00000028800, ENSCAFG00845004966, ENSMMUG00000009948
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HDAC1 cDNA Clones/ORF Plasmid
HDAC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3065 | Pre-made Human HDAC1/HD1/RPD3 siRNA oligo Duplex | 3065 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo297893 | Pre-made Rat Hdac1 siRNA oligo Duplex | 297893 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo433759 | Pre-made Mouse Hdac1/HD1/RPD3 siRNA oligo Duplex | 433759 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708441 | Pre-made Cynomolgus/Rhesus macaque HDAC1 siRNA oligo Duplex | 708441 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099228 | Pre-made Cat/Feline HDAC1 siRNA oligo Duplex | 101099228 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487309 | Pre-made Dog/Canine HDAC1 siRNA oligo Duplex | 487309 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404126 | Pre-made Bovines/Cattle HDAC1 siRNA oligo Duplex | 404126 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070281 | Pre-made Equine/Horse HDAC1 siRNA oligo Duplex | 100070281 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HDAC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68547-Ab | Human | Anti-Human HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T68547-Ab | Rat | Anti-Rat HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T68547-Ab | Mouse | Anti-Mouse HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T68547-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T68547-Ab | Cat/Feline | Anti-Cat/Feline HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T68547-Ab | Dog/Canine | Anti-Dog/Canine HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T68547-Ab | Bovines/Cattle | Anti-Bovines/Cattle HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T68547-Ab | Equine/Horse | Anti-Equine/Horse HDAC1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HDAC1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68547-Ag | Human | Human HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T68547-Ag | Rat | Rat HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T68547-Ag | Mouse | Mouse HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T68547-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T68547-Ag | Cat/Feline | Cat/Feline HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T68547-Ag | Dog/Canine | Dog/Canine HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T68547-Ag | Bovines/Cattle | Bovines/Cattle HDAC1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T68547-Ag | Equine/Horse | Equine/Horse HDAC1 recombinant protein | Mammalian cell | Detail |
