Recombinant multi-species CXCL11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
The Alternative Names of target: Beta-R1,C-X-C motif chemokine 11,CXCL11,Cxcl11,H174,I-TAC,IP-9,IP9,Interferon gamma-inducible protein 9 (IP-9),Interferon-inducible T-cell alpha chemoattractant (I-TAC),SCYB11,SCYB9B,Small-inducible cytokine B11,b-R1

Target products collectionGo to CXCL11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T68465-Ag-1/ GM-Tg-hg-T68465-Ag-2 Human CXCL11 protein Human
GM-Tg-rg-T68465-Ag-1/ GM-Tg-rg-T68465-Ag-2 Rat CXCL11 protein Rat
GM-Tg-mg-T68465-Ag-1/ GM-Tg-mg-T68465-Ag-2 Mouse CXCL11 protein Mouse
GM-Tg-cynog-T68465-Ag-1/ GM-Tg-cynog-T68465-Ag-2 Cynomolgus/Rhesus macaque CXCL11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T68465-Ag-1/ GM-Tg-felg-T68465-Ag-2 Feline CXCL11 protein Feline
GM-Tg-cang-T68465-Ag-1/ GM-Tg-cang-T68465-Ag-2 Canine CXCL11 protein Canine
GM-Tg-bovg-T68465-Ag-1/ GM-Tg-bovg-T68465-Ag-2 Bovine CXCL11 protein Bovine
GM-Tg-equg-T68465-Ag-1/ GM-Tg-equg-T68465-Ag-2 Equine CXCL11 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T68465-Ag-1/ GM-Tg-hg-T68465-Ag-2; GM-Tg-rg-T68465-Ag-1/ GM-Tg-rg-T68465-Ag-2;
GM-Tg-mg-T68465-Ag-1/ GM-Tg-mg-T68465-Ag-2; GM-Tg-cynog-T68465-Ag-1/ GM-Tg-cynog-T68465-Ag-2;
GM-Tg-felg-T68465-Ag-1/ GM-Tg-felg-T68465-Ag-2; GM-Tg-cang-T68465-Ag-1/ GM-Tg-cang-T68465-Ag-2;
GM-Tg-bovg-T68465-Ag-1/ GM-Tg-bovg-T68465-Ag-2; GM-Tg-equg-T68465-Ag-1/ GM-Tg-equg-T68465-Ag-2
Products Name CXCL11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CXCL11
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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