Recombinant multi-species PI3 Kinase p110 Delta/PIK3CD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Delta/PIK3CD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]
The Alternative Names of target: 2410099E07Rik,2610208K16Rik,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta (PtdIns-3-kinase subunit p110-delta,5-bisphosphate 3-kinase catalytic subunit delta isoform,APDS,IMD14,IMD14A,IMD14B,P110DELTA,PI3 Kinase p110 Delta,PI3-kinase subunit delta,PI3K,PI3K-delta,PI3Kdelta,PIK3CD,Phosphatidylinositol 4,Pik3cd,PtdIns-3-kinase subunit delta,ROCHIS,p110D,p110delta,p110delta)

Target products collectionGo to PI3 Kinase p110 Delta/PIK3CD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T67849-Ag-1/ GM-Tg-hg-T67849-Ag-2 Human PI3 Kinase p110 Delta/PIK3CD protein Human
GM-Tg-rg-T67849-Ag-1/ GM-Tg-rg-T67849-Ag-2 Rat PI3 Kinase p110 Delta/PIK3CD protein Rat
GM-Tg-mg-T67849-Ag-1/ GM-Tg-mg-T67849-Ag-2 Mouse PI3 Kinase p110 Delta/PIK3CD protein Mouse
GM-Tg-cynog-T67849-Ag-1/ GM-Tg-cynog-T67849-Ag-2 Cynomolgus/Rhesus macaque PI3 Kinase p110 Delta/PIK3CD protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T67849-Ag-1/ GM-Tg-felg-T67849-Ag-2 Feline PI3 Kinase p110 Delta/PIK3CD protein Feline
GM-Tg-cang-T67849-Ag-1/ GM-Tg-cang-T67849-Ag-2 Canine PI3 Kinase p110 Delta/PIK3CD protein Canine
GM-Tg-bovg-T67849-Ag-1/ GM-Tg-bovg-T67849-Ag-2 Bovine PI3 Kinase p110 Delta/PIK3CD protein Bovine
GM-Tg-equg-T67849-Ag-1/ GM-Tg-equg-T67849-Ag-2 Equine PI3 Kinase p110 Delta/PIK3CD protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T67849-Ag-1/ GM-Tg-hg-T67849-Ag-2; GM-Tg-rg-T67849-Ag-1/ GM-Tg-rg-T67849-Ag-2;
GM-Tg-mg-T67849-Ag-1/ GM-Tg-mg-T67849-Ag-2; GM-Tg-cynog-T67849-Ag-1/ GM-Tg-cynog-T67849-Ag-2;
GM-Tg-felg-T67849-Ag-1/ GM-Tg-felg-T67849-Ag-2; GM-Tg-cang-T67849-Ag-1/ GM-Tg-cang-T67849-Ag-2;
GM-Tg-bovg-T67849-Ag-1/ GM-Tg-bovg-T67849-Ag-2; GM-Tg-equg-T67849-Ag-1/ GM-Tg-equg-T67849-Ag-2
Products Name PI3 Kinase p110 Delta/PIK3CD protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PI3 Kinase p110 Delta/PIK3CD
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Delta/PIK3CD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.