Recombinant multi-species SERPIND1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SERPIND1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]
The Alternative Names of target: D22S673,HC-II,HC2,HCF2,HCII,HLS2,Hcf2,Heparin cofactor 2,Heparin cofactor II (HC-II),LS2,Protease inhibitor leuserpin-2 (HLS2),SERPIND1,Serpin D1,Serpind1,THPH10,rls2var1

Target products collectionGo to SERPIND1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T67258-Ag-1/ GM-Tg-hg-T67258-Ag-2 Human SERPIND1 protein Human
GM-Tg-rg-T67258-Ag-1/ GM-Tg-rg-T67258-Ag-2 Rat SERPIND1 protein Rat
GM-Tg-mg-T67258-Ag-1/ GM-Tg-mg-T67258-Ag-2 Mouse SERPIND1 protein Mouse
GM-Tg-cynog-T67258-Ag-1/ GM-Tg-cynog-T67258-Ag-2 Cynomolgus/Rhesus macaque SERPIND1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T67258-Ag-1/ GM-Tg-felg-T67258-Ag-2 Feline SERPIND1 protein Feline
GM-Tg-cang-T67258-Ag-1/ GM-Tg-cang-T67258-Ag-2 Canine SERPIND1 protein Canine
GM-Tg-bovg-T67258-Ag-1/ GM-Tg-bovg-T67258-Ag-2 Bovine SERPIND1 protein Bovine
GM-Tg-equg-T67258-Ag-1/ GM-Tg-equg-T67258-Ag-2 Equine SERPIND1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T67258-Ag-1/ GM-Tg-hg-T67258-Ag-2; GM-Tg-rg-T67258-Ag-1/ GM-Tg-rg-T67258-Ag-2;
GM-Tg-mg-T67258-Ag-1/ GM-Tg-mg-T67258-Ag-2; GM-Tg-cynog-T67258-Ag-1/ GM-Tg-cynog-T67258-Ag-2;
GM-Tg-felg-T67258-Ag-1/ GM-Tg-felg-T67258-Ag-2; GM-Tg-cang-T67258-Ag-1/ GM-Tg-cang-T67258-Ag-2;
GM-Tg-bovg-T67258-Ag-1/ GM-Tg-bovg-T67258-Ag-2; GM-Tg-equg-T67258-Ag-1/ GM-Tg-equg-T67258-Ag-2
Products Name SERPIND1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SERPIND1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SERPIND1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.