Explore SERPIND1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]
| Target ID |
GM-T67258
|
| Target Name |
SERPIND1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3053
|
| Gene ID |
100125764 (Bos taurus), 100629879 (Equus caballus), 100682658 (Canis lupus familiaris), 101085836 (Felis catus)
15160 (Mus musculus), 3053 (Homo sapiens), 696950 (Macaca mulatta), 79224 (Rattus norvegicus)
|
| Target Alternative Names |
D22S673,HC-II,HC2,HCF2,HCII,HLS2,Hcf2,Heparin cofactor 2,Heparin cofactor II (HC-II),LS2,Protease inhibitor leuserpin-2 (HLS2),SERPIND1,Serpin D1,Serpind1,THPH10,rls2var1
|
| Uniprot Accession |
P49182,P05546,Q64268
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Complement and coagulation cascades
|
| Gene Ensembl |
ENSBTAG00000013973, ENSECAG00000013924, ENSCAFG00845025426, ENSMUSG00000022766, ENSG00000099937, ENSMMUG00000022169
|
Pre-made viral vector of SERPIND1 cDNA Clones/ORF Plasmid
SERPIND1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3053 | Pre-made Human SERPIND1/HC2/LS2 siRNA oligo Duplex | 3053 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79224 | Pre-made Rat Serpind1/rls2var1 siRNA oligo Duplex | 79224 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15160 | Pre-made Mouse Serpind1/HCII/Hcf2 siRNA oligo Duplex | 15160 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696950 | Pre-made Cynomolgus/Rhesus macaque SERPIND1 siRNA oligo Duplex | 696950 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085836 | Pre-made Cat/Feline SERPIND1 siRNA oligo Duplex | 101085836 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100682658 | Pre-made Dog/Canine SERPIND1 siRNA oligo Duplex | 100682658 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100125764 | Pre-made Bovines/Cattle SERPIND1 siRNA oligo Duplex | 100125764 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100629879 | Pre-made Equine/Horse SERPIND1 siRNA oligo Duplex | 100629879 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SERPIND1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T67258-Ab | Human | Anti-Human SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T67258-Ab | Rat | Anti-Rat SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T67258-Ab | Mouse | Anti-Mouse SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T67258-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T67258-Ab | Cat/Feline | Anti-Cat/Feline SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T67258-Ab | Dog/Canine | Anti-Dog/Canine SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T67258-Ab | Bovines/Cattle | Anti-Bovines/Cattle SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T67258-Ab | Equine/Horse | Anti-Equine/Horse SERPIND1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SERPIND1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T67258-Ag | Human | Human SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T67258-Ag | Rat | Rat SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T67258-Ag | Mouse | Mouse SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T67258-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T67258-Ag | Cat/Feline | Cat/Feline SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T67258-Ag | Dog/Canine | Dog/Canine SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T67258-Ag | Bovines/Cattle | Bovines/Cattle SERPIND1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T67258-Ag | Equine/Horse | Equine/Horse SERPIND1 recombinant protein | Mammalian cell | Detail |
