Recombinant multi-species COX2/Cyclooxygenase 2/PTGS2/COX-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX2/Cyclooxygenase 2/PTGS2/COX-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
The Alternative Names of target: COX-2,COX2,Cox-2,Cox2,Cyclooxygenase 2,Cyclooxygenase-2 (COX-2),GRIPGHS,PES-2,PGG/HS,PGH2S,PGHS-2,PGHS-2),PGHS2,PHS II,PHS-2,PTGS2,Pghs2,Prostaglandin G/H synthase 2,Prostaglandin H2 synthase 2 (PGH synthase 2,Prostaglandin-endoperoxide synthase 2,Ptgs2,TIS10,gripghs,hCox-2

Target products collectionGo to COX2/Cyclooxygenase 2/PTGS2/COX-2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T66665-Ag-1/ GM-Tg-hg-T66665-Ag-2 Human COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Human
GM-Tg-rg-T66665-Ag-1/ GM-Tg-rg-T66665-Ag-2 Rat COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Rat
GM-Tg-mg-T66665-Ag-1/ GM-Tg-mg-T66665-Ag-2 Mouse COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Mouse
GM-Tg-cynog-T66665-Ag-1/ GM-Tg-cynog-T66665-Ag-2 Cynomolgus/Rhesus macaque COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T66665-Ag-1/ GM-Tg-felg-T66665-Ag-2 Feline COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Feline
GM-Tg-cang-T66665-Ag-1/ GM-Tg-cang-T66665-Ag-2 Canine COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Canine
GM-Tg-bovg-T66665-Ag-1/ GM-Tg-bovg-T66665-Ag-2 Bovine COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Bovine
GM-Tg-equg-T66665-Ag-1/ GM-Tg-equg-T66665-Ag-2 Equine COX2/Cyclooxygenase 2/PTGS2/COX-2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T66665-Ag-1/ GM-Tg-hg-T66665-Ag-2; GM-Tg-rg-T66665-Ag-1/ GM-Tg-rg-T66665-Ag-2;
GM-Tg-mg-T66665-Ag-1/ GM-Tg-mg-T66665-Ag-2; GM-Tg-cynog-T66665-Ag-1/ GM-Tg-cynog-T66665-Ag-2;
GM-Tg-felg-T66665-Ag-1/ GM-Tg-felg-T66665-Ag-2; GM-Tg-cang-T66665-Ag-1/ GM-Tg-cang-T66665-Ag-2;
GM-Tg-bovg-T66665-Ag-1/ GM-Tg-bovg-T66665-Ag-2; GM-Tg-equg-T66665-Ag-1/ GM-Tg-equg-T66665-Ag-2
Products Name COX2/Cyclooxygenase 2/PTGS2/COX-2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COX2/Cyclooxygenase 2/PTGS2/COX-2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX2/Cyclooxygenase 2/PTGS2/COX-2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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