Recombinant multi-species PKM2/PKM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKM2/PKM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
The Alternative Names of target: CTHBP,Cytosolic thyroid hormone-binding protein (CTHBP),HEL-S-30,OIP3,Opa-interacting protein 3 (OIP-3),PK,PK3,PKM,PKM12,PKM2,Pk-2,Pk-3,Pk3,Pkm,Pkm2,Pyruvate kinase 2/3,Pyruvate kinase PKM,Pyruvate kinase muscle isozyme,TCB,THBP1,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1 (THBP1),Tumor M2-PK,Tyrosine-protein kinase PKM2,p58

Target products collectionGo to PKM2/PKM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T65889-Ag-1/ GM-Tg-hg-T65889-Ag-2 Human PKM2/PKM protein Human
GM-Tg-rg-T65889-Ag-1/ GM-Tg-rg-T65889-Ag-2 Rat PKM2/PKM protein Rat
GM-Tg-mg-T65889-Ag-1/ GM-Tg-mg-T65889-Ag-2 Mouse PKM2/PKM protein Mouse
GM-Tg-cynog-T65889-Ag-1/ GM-Tg-cynog-T65889-Ag-2 Cynomolgus/Rhesus macaque PKM2/PKM protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T65889-Ag-1/ GM-Tg-felg-T65889-Ag-2 Feline PKM2/PKM protein Feline
GM-Tg-cang-T65889-Ag-1/ GM-Tg-cang-T65889-Ag-2 Canine PKM2/PKM protein Canine
GM-Tg-bovg-T65889-Ag-1/ GM-Tg-bovg-T65889-Ag-2 Bovine PKM2/PKM protein Bovine
GM-Tg-equg-T65889-Ag-1/ GM-Tg-equg-T65889-Ag-2 Equine PKM2/PKM protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T65889-Ag-1/ GM-Tg-hg-T65889-Ag-2; GM-Tg-rg-T65889-Ag-1/ GM-Tg-rg-T65889-Ag-2;
GM-Tg-mg-T65889-Ag-1/ GM-Tg-mg-T65889-Ag-2; GM-Tg-cynog-T65889-Ag-1/ GM-Tg-cynog-T65889-Ag-2;
GM-Tg-felg-T65889-Ag-1/ GM-Tg-felg-T65889-Ag-2; GM-Tg-cang-T65889-Ag-1/ GM-Tg-cang-T65889-Ag-2;
GM-Tg-bovg-T65889-Ag-1/ GM-Tg-bovg-T65889-Ag-2; GM-Tg-equg-T65889-Ag-1/ GM-Tg-equg-T65889-Ag-2
Products Name PKM2/PKM protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PKM2/PKM
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PKM2/PKM protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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