PKM2/PKM Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PKM2/PKM gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Target ID	GM-T65889
Target Name	PKM2/PKM
Gene Group ldentifer （Target Gene ID in Homo species)	5315
Gene ID	100063687 (Equus caballus), 123378905 (Felis catus), 18746 (Mus musculus), 25630 (Rattus norvegicus) 403874 (Canis lupus familiaris), 512571 (Bos taurus), 5315 (Homo sapiens), 697742 (Macaca mulatta)
Target Alternative Names	CTHBP,Cytosolic thyroid hormone-binding protein (CTHBP),HEL-S-30,OIP3,Opa-interacting protein 3 (OIP-3),PK,PK3,PKM,PKM12,PKM2,Pk-2,Pk-3,Pk3,Pkm,Pkm2,Pyruvate kinase 2/3,Pyruvate kinase PKM,Pyruvate kinase muscle isozyme,TCB,THBP1,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1 (THBP1),Tumor M2-PK,Tyrosine-protein kinase PKM2,p58
Uniprot Accession	P52480,P11980,P14618
Protein Sub-location	Secreted Protein/Potential Cytokines
Category	Therapeutics Target
Disease	Congenital occlusion of ureteropelvic junction
Disease from KEGG	Metabolic pathways, Type II diabetes mellitus, Human papillomavirus infection, Central carbon metabolism in cancer
Gene Ensembl	ENSECAG00000007644, ENSMUSG00000032294, ENSCAFG00845023630, ENSBTAG00000001601, ENSG00000067225, ENSMMUG00000023454

Pre-made viral vector of PKM2/PKM cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP004006	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.5	5315	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP004006	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.5	5315	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC000247	Human PKM/CTHBP/HEL-S-30 Mammalian (Non-Viral Vector) plasmid	NM_002654.6	5315	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	1xflag (C-Terminal)	EF1	Detail
vGMLV002409	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
pGMPC000827	Human PKM/CTHBP/HEL-S-30 Mammalian (Non-Viral Vector) plasmid	NM_002654	5315	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	Null	CMV	Detail
pGMLV001018	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC001349	Human PKM/CTHBP/HEL-S-30 Mammalian (Non-Viral Vector) plasmid	NM_002654.6	5315	Human	Mammalian (Non-Viral Vector) plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMPC001681	Human PKM/CTHBP/HEL-S-30 Mammalian (Non-Viral Vector) plasmid	NM_002654.6	5315	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	6xHis (C-Terminal)	CMV	Detail
vGMLV002407	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001018	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAD001486	Human PKM/CTHBP/HEL-S-30 Adenovirus particle	NM_002654.6	5315	Human	Adenovirus particle	EGFP	6xHis (C-Terminal)	EF1	Detail
vGMLV001109	Human mcherry-PKM1/CTHBP/HEL-S-30 Lentivirus particle	NM_182470.3	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001110	Human mCherry-PKM2/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001112	Human eGFP-PKM1/CTHBP/HEL-S-30 Lentivirus particle	NM_182470.3	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001238	Human eGFP-PKM1 /CTHBP/HEL-S-30 Lentivirus particle	NM_182470.3	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001241	Human mcherry-PKM1/CTHBP/HEL-S-30 Lentivirus particle	NM_182470.3	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001344	Human mCherry-PKM2/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001345	Human eGFP-PKM2/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001467	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMLV001604	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
vGMAD000966	Human PKM/CTHBP/HEL-S-30 Adenovirus particle	NM_002654.6	5315	Human	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMAD001486	Human PKM/CTHBP/HEL-S-30 Adenovirus plasmid	NM_002654.6	5315	Human	Adenovirus plasmid	EGFP	6xHis (C-Terminal)	EF1	Detail
pGMAD000966	Human PKM/CTHBP/HEL-S-30 Adenovirus plasmid	NM_002654.6	5315	Human	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMLV001109	Human mcherry-PKM1/CTHBP/HEL-S-30 Lentivirus plasmid	NM_182470.3	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001110	Human mCherry-PKM2/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001112	Human eGFP-PKM1/CTHBP/HEL-S-30 Lentivirus plasmid	NM_182470.3	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001238	Human eGFP-PKM1 /CTHBP/HEL-S-30 Lentivirus plasmid	NM_182470.3	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001241	Human mcherry-PKM1/CTHBP/HEL-S-30 Lentivirus plasmid	NM_182470.3	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001344	Human mCherry-PKM2/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001345	Human eGFP-PKM2/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001467	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001468	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV001604	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
pGMLV002407	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
vGMLV001468	Human PKM/CTHBP/HEL-S-30 Lentivirus particle	NM_002654.6	5315	Human	Lentivirus particle	Null	Null	CMV	Detail
pGMLV002409	Human PKM/CTHBP/HEL-S-30 Lentivirus plasmid	NM_002654.6	5315	Human	Lentivirus plasmid	Null	Null	CMV	Detail
vGMAAV001389	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) particle	NM_011099.3	18746	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV001388	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) particle	NM_011099.3	18746	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	NPHS1	Detail
vGMAAV001240	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) particle	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	TH	Detail
vGMAAV000762	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) particle	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) particle	Null	Null	CTNT	Detail
vGMAAV000540	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) particle	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) particle	Null	Null	CMV	Detail
vGMLV002422	Mouse Pkm/AA414905/AL024370 Lentivirus particle	NM_011099.3	18746	Mouse	Lentivirus particle	Null	3xflag (C-Terminal)	CMV	Detail
vGMAD000100	Mouse Pkm/AA414905/AL024370 Adenovirus particle	NM_001253883.1	18746	Mouse	Adenovirus particle	Null	3xflag (C-Terminal)	CMV	Detail
vGMAD000245	Mouse Pkm/AA414905/AL024370 Adenovirus particle	NM_011099.3	18746	Mouse	Adenovirus particle	Null	Null	CMV	Detail
vGMAD000432	Mouse Pkm/AA414905/AL024370 Adenovirus particle	NM_001253883.1	18746	Mouse	Adenovirus particle	Null	3xflag (C-Terminal)	CMV	Detail
vGMAD000766	Mouse Pkm/AA414905/AL024370 Adenovirus particle	NM_011099.4	18746	Mouse	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMAD001524	Mouse Pkm/Pk-2/Pk-3 Adenovirus particle	NM_011099	18746	Mouse	Adenovirus particle	EGFP	Null	EF1	Detail
pGMPC001233	Mouse Pkm/Pk-2/Pk-3 Mammalian (Non-Viral Vector) plasmid	NM_011099.4	18746	Mouse	Mammalian (Non-Viral Vector) plasmid	mCherry	HA (C-Terminal)	CMV	Detail
vGMLV001949	Mouse Pkm/AA414905/AL024370 Lentivirus particle	NM_011099.3	18746	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD001524	Mouse Pkm/Pk-2/Pk-3 Adenovirus plasmid	NM_011099	18746	Mouse	Adenovirus plasmid	EGFP	Null	EF1	Detail
pGMLV001949	Mouse Pkm/AA414905/AL024370 Lentivirus plasmid	NM_011099.3	18746	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002422	Mouse Pkm/AA414905/AL024370 Lentivirus plasmid	NM_011099.3	18746	Mouse	Lentivirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMAD000100	Mouse Pkm/AA414905/AL024370 Adenovirus plasmid	NM_001253883.1	18746	Mouse	Adenovirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMAD000245	Mouse Pkm/AA414905/AL024370 Adenovirus plasmid	NM_011099.3	18746	Mouse	Adenovirus plasmid	Null	Null	CMV	Detail
pGMAD000432	Mouse Pkm/AA414905/AL024370 Adenovirus plasmid	NM_001253883.1	18746	Mouse	Adenovirus plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMAD000766	Mouse Pkm/AA414905/AL024370 Adenovirus plasmid	NM_011099.4	18746	Mouse	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMAAV000540	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) plasmid	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) plasmid	Null	Null	CMV	Detail
pGMPC001698	Mouse Pkm/Pk-2/Pk-3 Mammalian (Non-Viral Vector) plasmid	NM_011099.4	18746	Mouse	Mammalian (Non-Viral Vector) plasmid	Null	3xflag (C-Terminal)	CMV	Detail
pGMAAV000762	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) plasmid	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) plasmid	Null	Null	CTNT	Detail
pGMAAV001240	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) plasmid	NM_011099.4	18746	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	TH	Detail
pGMAAV001388	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) plasmid	NM_011099.3	18746	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	NPHS1	Detail
pGMAAV001389	Mouse Pkm/AA414905/AL024370 Adeno-associate virus(AAV) plasmid	NM_011099.3	18746	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV002024	Mouse Pkm/Pk-2/Pk-3 Adeno-associate virus(AAV) plasmid	NM_001378868.1	18746	Mouse	Adeno-associate virus(AAV) plasmid	ZsGreen	3xflag (C-Terminal)	TCF21	Detail
pGMPC000672	Mouse Pkm/AA414905/AL024370 Mammalian (Non-Viral Vector) plasmid	NM_011099.4	18746	Mouse	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV002024	Mouse Pkm/Pk-2/Pk-3 Adeno-associate virus(AAV) particle	NM_001378868.1	18746	Mouse	Adeno-associate virus(AAV) particle	ZsGreen	3xflag (C-Terminal)	TCF21	Detail

PKM2/PKM siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo5315	Pre-made Human PKM/PK3/TCB siRNA oligo Duplex	5315	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo25630	Pre-made Rat Pkm/PK/Pk3 siRNA oligo Duplex	25630	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo18746	Pre-made Mouse Pkm/Pk3/Pk-2 siRNA oligo Duplex	18746	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo697742	Pre-made Cynomolgus/Rhesus macaque PKM/PKM2 siRNA oligo Duplex	697742	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo123378905	Pre-made Cat/Feline PKM siRNA oligo Duplex	123378905	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo403874	Pre-made Dog/Canine PKM siRNA oligo Duplex	403874	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo512571	Pre-made Bovines/Cattle PKM siRNA oligo Duplex	512571	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100063687	Pre-made Equine/Horse PKM/PKM2 siRNA oligo Duplex	100063687	Equine/Horse	In-vitro grade; in-vivo grade	Detail

PKM2/PKM antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T65889-Ab	Human	Anti-Human PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-rg-T65889-Ab	Rat	Anti-Rat PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-mg-T65889-Ab	Mouse	Anti-Mouse PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-cynog-T65889-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-felg-T65889-Ab	Cat/Feline	Anti-Cat/Feline PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-cang-T65889-Ab	Dog/Canine	Anti-Dog/Canine PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-bovg-T65889-Ab	Bovines/Cattle	Anti-Bovines/Cattle PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-equg-T65889-Ab	Equine/Horse	Anti-Equine/Horse PKM2/PKM monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail

PKM2/PKM recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T65889-Ag	Human	Human PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T65889-Ag	Rat	Rat PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T65889-Ag	Mouse	Mouse PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T65889-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T65889-Ag	Cat/Feline	Cat/Feline PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T65889-Ag	Dog/Canine	Dog/Canine PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T65889-Ag	Bovines/Cattle	Bovines/Cattle PKM2/PKM recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T65889-Ag	Equine/Horse	Equine/Horse PKM2/PKM recombinant protein	Mammalian cell	Detail