Recombinant multi-species NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
The Alternative Names of target: 6030402G23Rik,ARIA,D230005F13Rik,GGF,GGF2,GGFII,HGL,HRG,HRG1,HRGA,HRGalpha,Hgl,MST131,MSTP131,NDF,NRG1,NRG1-IT2,Nrg1,Pro-NRG1,Pro-neuregulin-1,SMDF,isoform Alpha,isoform Beta1,isoform SMDF,membrane-bound isoform

Target products collectionGo to NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T65198-Ag-1/ GM-Tg-hg-T65198-Ag-2 Human NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Human
GM-Tg-rg-T65198-Ag-1/ GM-Tg-rg-T65198-Ag-2 Rat NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Rat
GM-Tg-mg-T65198-Ag-1/ GM-Tg-mg-T65198-Ag-2 Mouse NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Mouse
GM-Tg-cynog-T65198-Ag-1/ GM-Tg-cynog-T65198-Ag-2 Cynomolgus/Rhesus macaque NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T65198-Ag-1/ GM-Tg-felg-T65198-Ag-2 Feline NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Feline
GM-Tg-cang-T65198-Ag-1/ GM-Tg-cang-T65198-Ag-2 Canine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Canine
GM-Tg-bovg-T65198-Ag-1/ GM-Tg-bovg-T65198-Ag-2 Bovine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Bovine
GM-Tg-equg-T65198-Ag-1/ GM-Tg-equg-T65198-Ag-2 Equine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T65198-Ag-1/ GM-Tg-hg-T65198-Ag-2; GM-Tg-rg-T65198-Ag-1/ GM-Tg-rg-T65198-Ag-2;
GM-Tg-mg-T65198-Ag-1/ GM-Tg-mg-T65198-Ag-2; GM-Tg-cynog-T65198-Ag-1/ GM-Tg-cynog-T65198-Ag-2;
GM-Tg-felg-T65198-Ag-1/ GM-Tg-felg-T65198-Ag-2; GM-Tg-cang-T65198-Ag-1/ GM-Tg-cang-T65198-Ag-2;
GM-Tg-bovg-T65198-Ag-1/ GM-Tg-bovg-T65198-Ag-2; GM-Tg-equg-T65198-Ag-1/ GM-Tg-equg-T65198-Ag-2
Products Name NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.