Explore NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
| Target ID |
GM-T65198
|
| Target Name |
NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3084
|
| Gene ID |
101096805 (Felis catus), 112400 (Rattus norvegicus), 211323 (Mus musculus), 281361 (Bos taurus)
3084 (Homo sapiens), 482861 (Canis lupus familiaris), 696275 (Macaca mulatta)
|
| Target Alternative Names |
6030402G23Rik,ARIA,D230005F13Rik,GGF,GGF2,GGFII,HGL,HRG,HRG1,HRGA,HRGalpha,Hgl,MST131,MSTP131,NDF,NRG1,NRG1-IT2,Nrg1,Pro-NRG1,Pro-neuregulin-1,SMDF,isoform Alpha,isoform Beta1,isoform SMDF,membrane-bound isoform
|
| Uniprot Accession |
P43322,Q6DR98,Q02297
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, ErbB signaling pathway
|
| Gene Ensembl |
ENSMUSG00000062991, ENSBTAG00000004150, ENSG00000157168, ENSCAFG00845014867, ENSMMUG00000000208
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 cDNA Clones/ORF Plasmid
NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3084 | Pre-made Human NRG1/GGF/HGL siRNA oligo Duplex | 3084 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo112400 | Pre-made Rat Nrg1 siRNA oligo Duplex | 112400 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo211323 | Pre-made Mouse Nrg1/GGF/HRG siRNA oligo Duplex | 211323 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696275 | Pre-made Cynomolgus/Rhesus macaque NRG1 siRNA oligo Duplex | 696275 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096805 | Pre-made Cat/Feline NRG1 siRNA oligo Duplex | 101096805 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482861 | Pre-made Dog/Canine NRG1 siRNA oligo Duplex | 482861 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281361 | Pre-made Bovines/Cattle NRG1 siRNA oligo Duplex | 281361 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T65198-Ab | Human | Anti-Human NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T65198-Ab | Rat | Anti-Rat NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T65198-Ab | Mouse | Anti-Mouse NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T65198-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T65198-Ab | Cat/Feline | Anti-Cat/Feline NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T65198-Ab | Dog/Canine | Anti-Dog/Canine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T65198-Ab | Bovines/Cattle | Anti-Bovines/Cattle NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T65198-Ag | Human | Human NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T65198-Ag | Rat | Rat NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T65198-Ag | Mouse | Mouse NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T65198-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T65198-Ag | Cat/Feline | Cat/Feline NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T65198-Ag | Dog/Canine | Dog/Canine NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T65198-Ag | Bovines/Cattle | Bovines/Cattle NRG1/isoform SMDF/isoform Alpha/isoform Beta1/Pro-NRG1 recombinant protein | Mammalian cell | Detail |
