Recombinant multi-species STAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]
The Alternative Names of target: 2010005J02Rik,CANDF7,DD6G4-4,IMD31A,IMD31B,IMD31C,ISGF-3,STAT1,STAT91,Signal transducer and activator of transcription 1-alpha/beta,Stat1,Transcription factor ISGF-3 components p91/p84

Target products collectionGo to STAT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T64205-Ag-1/ GM-Tg-hg-T64205-Ag-2 Human STAT1 protein Human
GM-Tg-rg-T64205-Ag-1/ GM-Tg-rg-T64205-Ag-2 Rat STAT1 protein Rat
GM-Tg-mg-T64205-Ag-1/ GM-Tg-mg-T64205-Ag-2 Mouse STAT1 protein Mouse
GM-Tg-cynog-T64205-Ag-1/ GM-Tg-cynog-T64205-Ag-2 Cynomolgus/Rhesus macaque STAT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T64205-Ag-1/ GM-Tg-felg-T64205-Ag-2 Feline STAT1 protein Feline
GM-Tg-cang-T64205-Ag-1/ GM-Tg-cang-T64205-Ag-2 Canine STAT1 protein Canine
GM-Tg-bovg-T64205-Ag-1/ GM-Tg-bovg-T64205-Ag-2 Bovine STAT1 protein Bovine
GM-Tg-equg-T64205-Ag-1/ GM-Tg-equg-T64205-Ag-2 Equine STAT1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T64205-Ag-1/ GM-Tg-hg-T64205-Ag-2; GM-Tg-rg-T64205-Ag-1/ GM-Tg-rg-T64205-Ag-2;
GM-Tg-mg-T64205-Ag-1/ GM-Tg-mg-T64205-Ag-2; GM-Tg-cynog-T64205-Ag-1/ GM-Tg-cynog-T64205-Ag-2;
GM-Tg-felg-T64205-Ag-1/ GM-Tg-felg-T64205-Ag-2; GM-Tg-cang-T64205-Ag-1/ GM-Tg-cang-T64205-Ag-2;
GM-Tg-bovg-T64205-Ag-1/ GM-Tg-bovg-T64205-Ag-2; GM-Tg-equg-T64205-Ag-1/ GM-Tg-equg-T64205-Ag-2
Products Name STAT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name STAT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STAT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.