Recombinant multi-species IFN alpha 2A/IFNA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFN alpha 2A/IFNA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]
The Alternative Names of target: IFN alpha 2A,IFN-alpha-2,IFN-alphaA,IFNA,IFNA2,IFNA2B,Interferon alpha-2,Interferon alpha-A (LeIF A),leIF A
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T63934-Ag-1/ GM-Tg-hg-T63934-Ag-2 | Human IFN alpha 2A/IFNA2 protein | Human |
| GM-Tg-rg-T63934-Ag-1/ GM-Tg-rg-T63934-Ag-2 | Rat IFN alpha 2A/IFNA2 protein | Rat |
| GM-Tg-mg-T63934-Ag-1/ GM-Tg-mg-T63934-Ag-2 | Mouse IFN alpha 2A/IFNA2 protein | Mouse |
| GM-Tg-cynog-T63934-Ag-1/ GM-Tg-cynog-T63934-Ag-2 | Cynomolgus/Rhesus macaque IFN alpha 2A/IFNA2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T63934-Ag-1/ GM-Tg-felg-T63934-Ag-2 | Feline IFN alpha 2A/IFNA2 protein | Feline |
| GM-Tg-cang-T63934-Ag-1/ GM-Tg-cang-T63934-Ag-2 | Canine IFN alpha 2A/IFNA2 protein | Canine |
| GM-Tg-bovg-T63934-Ag-1/ GM-Tg-bovg-T63934-Ag-2 | Bovine IFN alpha 2A/IFNA2 protein | Bovine |
| GM-Tg-equg-T63934-Ag-1/ GM-Tg-equg-T63934-Ag-2 | Equine IFN alpha 2A/IFNA2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T63934-Ag-1/ GM-Tg-hg-T63934-Ag-2;
GM-Tg-rg-T63934-Ag-1/ GM-Tg-rg-T63934-Ag-2;
GM-Tg-mg-T63934-Ag-1/ GM-Tg-mg-T63934-Ag-2; GM-Tg-cynog-T63934-Ag-1/ GM-Tg-cynog-T63934-Ag-2; GM-Tg-felg-T63934-Ag-1/ GM-Tg-felg-T63934-Ag-2; GM-Tg-cang-T63934-Ag-1/ GM-Tg-cang-T63934-Ag-2; GM-Tg-bovg-T63934-Ag-1/ GM-Tg-bovg-T63934-Ag-2; GM-Tg-equg-T63934-Ag-1/ GM-Tg-equg-T63934-Ag-2 |
| Products Name | IFN alpha 2A/IFNA2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | IFN alpha 2A/IFNA2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IFN alpha 2A/IFNA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.