Recombinant multi-species RAD51 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
The Alternative Names of target: BRCC5,CRAD51,DNA repair protein RAD51 homolog 1,FANCR,HRAD51,HsRAD51,HsRad51,HsT16930,MRMV2,RAD51,RAD51 homolog A,RAD51A,RECA,RGD1563603,Rad51,Rad51a,Reca,hRAD51

Target products collectionGo to RAD51 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T63083-Ag-1/ GM-Tg-hg-T63083-Ag-2 Human RAD51 protein Human
GM-Tg-rg-T63083-Ag-1/ GM-Tg-rg-T63083-Ag-2 Rat RAD51 protein Rat
GM-Tg-mg-T63083-Ag-1/ GM-Tg-mg-T63083-Ag-2 Mouse RAD51 protein Mouse
GM-Tg-cynog-T63083-Ag-1/ GM-Tg-cynog-T63083-Ag-2 Cynomolgus/Rhesus macaque RAD51 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T63083-Ag-1/ GM-Tg-felg-T63083-Ag-2 Feline RAD51 protein Feline
GM-Tg-cang-T63083-Ag-1/ GM-Tg-cang-T63083-Ag-2 Canine RAD51 protein Canine
GM-Tg-bovg-T63083-Ag-1/ GM-Tg-bovg-T63083-Ag-2 Bovine RAD51 protein Bovine
GM-Tg-equg-T63083-Ag-1/ GM-Tg-equg-T63083-Ag-2 Equine RAD51 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T63083-Ag-1/ GM-Tg-hg-T63083-Ag-2; GM-Tg-rg-T63083-Ag-1/ GM-Tg-rg-T63083-Ag-2;
GM-Tg-mg-T63083-Ag-1/ GM-Tg-mg-T63083-Ag-2; GM-Tg-cynog-T63083-Ag-1/ GM-Tg-cynog-T63083-Ag-2;
GM-Tg-felg-T63083-Ag-1/ GM-Tg-felg-T63083-Ag-2; GM-Tg-cang-T63083-Ag-1/ GM-Tg-cang-T63083-Ag-2;
GM-Tg-bovg-T63083-Ag-1/ GM-Tg-bovg-T63083-Ag-2; GM-Tg-equg-T63083-Ag-1/ GM-Tg-equg-T63083-Ag-2
Products Name RAD51 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RAD51
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD51 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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