Recombinant multi-species TBK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. [provided by RefSeq, Sep 2021]
The Alternative Names of target: 1200008B05Rik,AIARV,FTDALS4,IIAE8,NAK,NF-kappa-B-activating kinase,Serine/threonine-protein kinase TBK1,T2K,TANK-binding kinase 1,TBK1,Tbk1

Target products collectionGo to TBK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T63024-Ag-1/ GM-Tg-hg-T63024-Ag-2 Human TBK1 protein Human
GM-Tg-rg-T63024-Ag-1/ GM-Tg-rg-T63024-Ag-2 Rat TBK1 protein Rat
GM-Tg-mg-T63024-Ag-1/ GM-Tg-mg-T63024-Ag-2 Mouse TBK1 protein Mouse
GM-Tg-cynog-T63024-Ag-1/ GM-Tg-cynog-T63024-Ag-2 Cynomolgus/Rhesus macaque TBK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T63024-Ag-1/ GM-Tg-felg-T63024-Ag-2 Feline TBK1 protein Feline
GM-Tg-cang-T63024-Ag-1/ GM-Tg-cang-T63024-Ag-2 Canine TBK1 protein Canine
GM-Tg-bovg-T63024-Ag-1/ GM-Tg-bovg-T63024-Ag-2 Bovine TBK1 protein Bovine
GM-Tg-equg-T63024-Ag-1/ GM-Tg-equg-T63024-Ag-2 Equine TBK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T63024-Ag-1/ GM-Tg-hg-T63024-Ag-2; GM-Tg-rg-T63024-Ag-1/ GM-Tg-rg-T63024-Ag-2;
GM-Tg-mg-T63024-Ag-1/ GM-Tg-mg-T63024-Ag-2; GM-Tg-cynog-T63024-Ag-1/ GM-Tg-cynog-T63024-Ag-2;
GM-Tg-felg-T63024-Ag-1/ GM-Tg-felg-T63024-Ag-2; GM-Tg-cang-T63024-Ag-1/ GM-Tg-cang-T63024-Ag-2;
GM-Tg-bovg-T63024-Ag-1/ GM-Tg-bovg-T63024-Ag-2; GM-Tg-equg-T63024-Ag-1/ GM-Tg-equg-T63024-Ag-2
Products Name TBK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TBK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.