TBK1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore TBK1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. [provided by RefSeq, Sep 2021]

Target ID GM-T63024
Target Name TBK1
Gene Group ldentifer
（Target Gene ID in Homo species) 		29110
Gene ID 100051650 (Equus caballus), 101091955 (Felis catus), 29110 (Homo sapiens), 299827 (Rattus norvegicus)
481145 (Canis lupus familiaris), 533141 (Bos taurus), 56480 (Mus musculus), 717427 (Macaca mulatta)
Target Alternative Names 1200008B05Rik,AIARV,FTDALS4,IIAE8,NAK,NF-kappa-B-activating kinase,Serine/threonine-protein kinase TBK1,T2K,TANK-binding kinase 1,TBK1,Tbk1
Uniprot Accession Q9UHD2,Q9WUN2
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Ras signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, IL-17 signaling pathway, Alcoholic liver disease, Yersinia infection, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Lipid and atherosclerosis
Gene Ensembl ENSECAG00000020820, ENSG00000183735, ENSCAFG00845011038, ENSBTAG00000017401, ENSMUSG00000020115, ENSMMUG00000007658
Target Classification Kinase


Pre-made viral vector of TBK1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001810Human TBK1/FTDALS4/NAK Lentivirus plasmidNM_01325429110HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005239Human TBK1/FTDALS4/IIAE8 Lentivirus plasmidNM_013254.329110HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005724Human TBK1/FTDALS4/IIAE8 Lentivirus plasmidNM_013254.329110HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV002474Human TBK1/FTDALS4/IIAE8 Lentivirus plasmidNM_013254.429110HumanLentivirus plasmidZsGreen3xflag (C-Terminal)EF1Detail
pGMPC000560Human TBK1/FTDALS4/IIAE8 Mammalian (Non-Viral Vector) plasmidNM_01325429110HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP001810Human TBK1/FTDALS4/NAK Lentivirus particleNM_01325429110HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005239Human TBK1/FTDALS4/IIAE8 Lentivirus particleNM_013254.329110HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005724Human TBK1/FTDALS4/IIAE8 Lentivirus particleNM_013254.329110HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV002474Human TBK1/FTDALS4/IIAE8 Lentivirus particleNM_013254.429110HumanLentivirus particleZsGreen3xflag (C-Terminal)EF1Detail
pGMLPm004299Mouse Tbk1/1200008B05Rik/AI462036 Lentivirus plasmidNM_01978656480MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm004299Mouse Tbk1/1200008B05Rik/AI462036 Lentivirus particleNM_01978656480MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


TBK1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo29110Pre-made Human TBK1/NAK/T2K siRNA oligo Duplex29110HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo299827Pre-made Rat Tbk1 siRNA oligo Duplex299827RatIn-vitro grade; in-vivo gradeDetail
pGMoligo56480Pre-made Mouse Tbk1/1200008B05Rik siRNA oligo Duplex56480MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo717427Pre-made Cynomolgus/Rhesus macaque TBK1 siRNA oligo Duplex717427Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101091955Pre-made Cat/Feline TBK1 siRNA oligo Duplex101091955Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo481145Pre-made Dog/Canine TBK1 siRNA oligo Duplex481145Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo533141Pre-made Bovines/Cattle TBK1 siRNA oligo Duplex533141Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100051650Pre-made Equine/Horse TBK1 siRNA oligo Duplex100051650Equine/HorseIn-vitro grade; in-vivo gradeDetail


TBK1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T63024-AbHumanAnti-Human TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T63024-AbRatAnti-Rat TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T63024-AbMouseAnti-Mouse TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T63024-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T63024-AbCat/FelineAnti-Cat/Feline TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T63024-AbDog/CanineAnti-Dog/Canine TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T63024-AbBovines/CattleAnti-Bovines/Cattle TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T63024-AbEquine/HorseAnti-Equine/Horse TBK1 monoclonal antibodymabTherapeutics Target antibodyDetail


TBK1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T63024-AgHumanHuman TBK1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T63024-AgRatRat TBK1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T63024-AgMouseMouse TBK1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T63024-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque TBK1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T63024-AgCat/FelineCat/Feline TBK1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T63024-AgDog/CanineDog/Canine TBK1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T63024-AgBovines/CattleBovines/Cattle TBK1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T63024-AgEquine/HorseEquine/Horse TBK1 recombinant proteinMammalian cellDetail