Recombinant multi-species ADRBK1/GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADRBK1/GRK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
The Alternative Names of target: ADRBK1,Adrbk-1,Adrbk1,BARK1,BETA-ARK1,Bark-1,Beta-ARK-1,Beta-adrenergic receptor kinase 1,G-protein coupled receptor kinase 2,GRK-2,GRK2,Grk2,beta ARK,betaARK1

Target products collectionGo to ADRBK1/GRK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T62548-Ag-1/ GM-Tg-hg-T62548-Ag-2 Human ADRBK1/GRK2 protein Human
GM-Tg-rg-T62548-Ag-1/ GM-Tg-rg-T62548-Ag-2 Rat ADRBK1/GRK2 protein Rat
GM-Tg-mg-T62548-Ag-1/ GM-Tg-mg-T62548-Ag-2 Mouse ADRBK1/GRK2 protein Mouse
GM-Tg-cynog-T62548-Ag-1/ GM-Tg-cynog-T62548-Ag-2 Cynomolgus/Rhesus macaque ADRBK1/GRK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T62548-Ag-1/ GM-Tg-felg-T62548-Ag-2 Feline ADRBK1/GRK2 protein Feline
GM-Tg-cang-T62548-Ag-1/ GM-Tg-cang-T62548-Ag-2 Canine ADRBK1/GRK2 protein Canine
GM-Tg-bovg-T62548-Ag-1/ GM-Tg-bovg-T62548-Ag-2 Bovine ADRBK1/GRK2 protein Bovine
GM-Tg-equg-T62548-Ag-1/ GM-Tg-equg-T62548-Ag-2 Equine ADRBK1/GRK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T62548-Ag-1/ GM-Tg-hg-T62548-Ag-2; GM-Tg-rg-T62548-Ag-1/ GM-Tg-rg-T62548-Ag-2;
GM-Tg-mg-T62548-Ag-1/ GM-Tg-mg-T62548-Ag-2; GM-Tg-cynog-T62548-Ag-1/ GM-Tg-cynog-T62548-Ag-2;
GM-Tg-felg-T62548-Ag-1/ GM-Tg-felg-T62548-Ag-2; GM-Tg-cang-T62548-Ag-1/ GM-Tg-cang-T62548-Ag-2;
GM-Tg-bovg-T62548-Ag-1/ GM-Tg-bovg-T62548-Ag-2; GM-Tg-equg-T62548-Ag-1/ GM-Tg-equg-T62548-Ag-2
Products Name ADRBK1/GRK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ADRBK1/GRK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADRBK1/GRK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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