Recombinant multi-species IL-2/IL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-2/IL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020]
The Alternative Names of target: IL-2,IL2,Il-2,Il2,Interleukin-2,T-cell growth factor (TCGF),TCGF,lymphokine

Target products collectionGo to IL-2/IL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T61698-Ag-1/ GM-Tg-hg-T61698-Ag-2 Human IL-2/IL2 protein Human
GM-Tg-rg-T61698-Ag-1/ GM-Tg-rg-T61698-Ag-2 Rat IL-2/IL2 protein Rat
GM-Tg-mg-T61698-Ag-1/ GM-Tg-mg-T61698-Ag-2 Mouse IL-2/IL2 protein Mouse
GM-Tg-cynog-T61698-Ag-1/ GM-Tg-cynog-T61698-Ag-2 Cynomolgus/Rhesus macaque IL-2/IL2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T61698-Ag-1/ GM-Tg-felg-T61698-Ag-2 Feline IL-2/IL2 protein Feline
GM-Tg-cang-T61698-Ag-1/ GM-Tg-cang-T61698-Ag-2 Canine IL-2/IL2 protein Canine
GM-Tg-bovg-T61698-Ag-1/ GM-Tg-bovg-T61698-Ag-2 Bovine IL-2/IL2 protein Bovine
GM-Tg-equg-T61698-Ag-1/ GM-Tg-equg-T61698-Ag-2 Equine IL-2/IL2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T61698-Ag-1/ GM-Tg-hg-T61698-Ag-2; GM-Tg-rg-T61698-Ag-1/ GM-Tg-rg-T61698-Ag-2;
GM-Tg-mg-T61698-Ag-1/ GM-Tg-mg-T61698-Ag-2; GM-Tg-cynog-T61698-Ag-1/ GM-Tg-cynog-T61698-Ag-2;
GM-Tg-felg-T61698-Ag-1/ GM-Tg-felg-T61698-Ag-2; GM-Tg-cang-T61698-Ag-1/ GM-Tg-cang-T61698-Ag-2;
GM-Tg-bovg-T61698-Ag-1/ GM-Tg-bovg-T61698-Ag-2; GM-Tg-equg-T61698-Ag-1/ GM-Tg-equg-T61698-Ag-2
Products Name IL-2/IL2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-2/IL2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-2/IL2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.