Recombinant multi-species RARB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RARB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]
The Alternative Names of target: A830025K23,HAP,HBV-activated protein,Hap,MCOPS12,NR1B2,Nr1b2,Nuclear receptor subfamily 1 group B member 2,RAR-beta,RAR-epsilon,RARB,RARbeta,RARbeta1,RRB2,Rarb,Retinoic acid receptor beta

Target products collectionGo to RARB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T61657-Ag-1/ GM-Tg-hg-T61657-Ag-2 Human RARB protein Human
GM-Tg-rg-T61657-Ag-1/ GM-Tg-rg-T61657-Ag-2 Rat RARB protein Rat
GM-Tg-mg-T61657-Ag-1/ GM-Tg-mg-T61657-Ag-2 Mouse RARB protein Mouse
GM-Tg-cynog-T61657-Ag-1/ GM-Tg-cynog-T61657-Ag-2 Cynomolgus/Rhesus macaque RARB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T61657-Ag-1/ GM-Tg-felg-T61657-Ag-2 Feline RARB protein Feline
GM-Tg-cang-T61657-Ag-1/ GM-Tg-cang-T61657-Ag-2 Canine RARB protein Canine
GM-Tg-bovg-T61657-Ag-1/ GM-Tg-bovg-T61657-Ag-2 Bovine RARB protein Bovine
GM-Tg-equg-T61657-Ag-1/ GM-Tg-equg-T61657-Ag-2 Equine RARB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T61657-Ag-1/ GM-Tg-hg-T61657-Ag-2; GM-Tg-rg-T61657-Ag-1/ GM-Tg-rg-T61657-Ag-2;
GM-Tg-mg-T61657-Ag-1/ GM-Tg-mg-T61657-Ag-2; GM-Tg-cynog-T61657-Ag-1/ GM-Tg-cynog-T61657-Ag-2;
GM-Tg-felg-T61657-Ag-1/ GM-Tg-felg-T61657-Ag-2; GM-Tg-cang-T61657-Ag-1/ GM-Tg-cang-T61657-Ag-2;
GM-Tg-bovg-T61657-Ag-1/ GM-Tg-bovg-T61657-Ag-2; GM-Tg-equg-T61657-Ag-1/ GM-Tg-equg-T61657-Ag-2
Products Name RARB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RARB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RARB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.