Explore RARB gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]
| Target ID |
GM-T61657
|
| Target Name |
RARB
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5915
|
| Gene ID |
100051546 (Equus caballus), 101085742 (Felis catus), 218772 (Mus musculus), 24706 (Rattus norvegicus) 477045 (Canis lupus familiaris), 5915 (Homo sapiens), 616895 (Bos taurus), 700485 (Macaca mulatta)
|
| Target Alternative Names |
A830025K23,HAP,HBV-activated protein,Hap,MCOPS12,NR1B2,Nr1b2,Nuclear receptor subfamily 1 group B member 2,RAR-beta,RAR-epsilon,RARB,RARbeta,RARbeta1,RRB2,Rarb,Retinoic acid receptor beta
|
| Uniprot Accession |
P22605,P10826
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Lung Cancer
|
| Disease from KEGG |
Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000016976, ENSMUSG00000017491, ENSCAFG00845019290, ENSG00000077092, ENSBTAG00000011518, ENSMMUG00000007367
|
| Target Classification |
Nuclear Receptors
|
Pre-made viral vector of RARB cDNA Clones/ORF Plasmid
RARB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5915 | Pre-made Human RARB/HAP/RRB2 siRNA oligo Duplex | 5915 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24706 | Pre-made Rat Rarb siRNA oligo Duplex | 24706 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo218772 | Pre-made Mouse Rarb/Hap/Nr1b2 siRNA oligo Duplex | 218772 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700485 | Pre-made Cynomolgus/Rhesus macaque RARB siRNA oligo Duplex | 700485 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085742 | Pre-made Cat/Feline RARB siRNA oligo Duplex | 101085742 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477045 | Pre-made Dog/Canine RARB siRNA oligo Duplex | 477045 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616895 | Pre-made Bovines/Cattle RARB siRNA oligo Duplex | 616895 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051546 | Pre-made Equine/Horse RARB siRNA oligo Duplex | 100051546 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RARB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T61657-Ab | Human | Anti-Human RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T61657-Ab | Rat | Anti-Rat RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T61657-Ab | Mouse | Anti-Mouse RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T61657-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T61657-Ab | Cat/Feline | Anti-Cat/Feline RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T61657-Ab | Dog/Canine | Anti-Dog/Canine RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T61657-Ab | Bovines/Cattle | Anti-Bovines/Cattle RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T61657-Ab | Equine/Horse | Anti-Equine/Horse RARB monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RARB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T61657-Ag | Human | Human RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T61657-Ag | Rat | Rat RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T61657-Ag | Mouse | Mouse RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T61657-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T61657-Ag | Cat/Feline | Cat/Feline RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T61657-Ag | Dog/Canine | Dog/Canine RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T61657-Ag | Bovines/Cattle | Bovines/Cattle RARB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T61657-Ag | Equine/Horse | Equine/Horse RARB recombinant protein | Mammalian cell | Detail |