Recombinant multi-species AKR1C3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKR1C3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
The Alternative Names of target: 17-beta-hydroxysteroid dehydrogenase type 5 (17-beta-HSD 5),3-alpha-HSD type II,3-alpha-hydroxysteroid dehydrogenase type 2 (3-alpha-HSD type 2),AKR1C3,Aldo-keto reductase family 1 member C3,Chlordecone reductase homolog HAKRb,DD3,DD3),DDX,Dihydrodiol dehydrogenase 3 (DD-3,Dihydrodiol dehydrogenase type I,HA1753,HAKRB,HAKRe,HSD17B5,PGFS,Prostaglandin F synthase (PGFS),Testosterone 17-beta-dehydrogenase 5,brain,hluPGFS

Target products collectionGo to AKR1C3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T60857-Ag-1/ GM-Tg-hg-T60857-Ag-2 Human AKR1C3 protein Human
GM-Tg-rg-T60857-Ag-1/ GM-Tg-rg-T60857-Ag-2 Rat AKR1C3 protein Rat
GM-Tg-mg-T60857-Ag-1/ GM-Tg-mg-T60857-Ag-2 Mouse AKR1C3 protein Mouse
GM-Tg-cynog-T60857-Ag-1/ GM-Tg-cynog-T60857-Ag-2 Cynomolgus/Rhesus macaque AKR1C3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T60857-Ag-1/ GM-Tg-felg-T60857-Ag-2 Feline AKR1C3 protein Feline
GM-Tg-cang-T60857-Ag-1/ GM-Tg-cang-T60857-Ag-2 Canine AKR1C3 protein Canine
GM-Tg-bovg-T60857-Ag-1/ GM-Tg-bovg-T60857-Ag-2 Bovine AKR1C3 protein Bovine
GM-Tg-equg-T60857-Ag-1/ GM-Tg-equg-T60857-Ag-2 Equine AKR1C3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T60857-Ag-1/ GM-Tg-hg-T60857-Ag-2; GM-Tg-rg-T60857-Ag-1/ GM-Tg-rg-T60857-Ag-2;
GM-Tg-mg-T60857-Ag-1/ GM-Tg-mg-T60857-Ag-2; GM-Tg-cynog-T60857-Ag-1/ GM-Tg-cynog-T60857-Ag-2;
GM-Tg-felg-T60857-Ag-1/ GM-Tg-felg-T60857-Ag-2; GM-Tg-cang-T60857-Ag-1/ GM-Tg-cang-T60857-Ag-2;
GM-Tg-bovg-T60857-Ag-1/ GM-Tg-bovg-T60857-Ag-2; GM-Tg-equg-T60857-Ag-1/ GM-Tg-equg-T60857-Ag-2
Products Name AKR1C3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AKR1C3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKR1C3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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