Recombinant multi-species OGDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OGDH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
The Alternative Names of target: 2-oxoglutarate dehydrogenase,2-oxoglutarate dehydrogenase complex component E1,2210403E04Rik,2210412K19Rik,AKGDH,Alpha-ketoglutarate dehydrogenase (Alpha-KGDH-E1),E1k,E1o,HsOGDH,KGD1,OGDC,OGDC-E1,OGDH,OGDH-E1,OGDH2,OGDHD,Ogdh,Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase,d1401,mKIAA4192,mitochondrial

Target products collectionGo to OGDH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T60636-Ag-1/ GM-Tg-hg-T60636-Ag-2 Human OGDH protein Human
GM-Tg-rg-T60636-Ag-1/ GM-Tg-rg-T60636-Ag-2 Rat OGDH protein Rat
GM-Tg-mg-T60636-Ag-1/ GM-Tg-mg-T60636-Ag-2 Mouse OGDH protein Mouse
GM-Tg-cynog-T60636-Ag-1/ GM-Tg-cynog-T60636-Ag-2 Cynomolgus/Rhesus macaque OGDH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T60636-Ag-1/ GM-Tg-felg-T60636-Ag-2 Feline OGDH protein Feline
GM-Tg-cang-T60636-Ag-1/ GM-Tg-cang-T60636-Ag-2 Canine OGDH protein Canine
GM-Tg-bovg-T60636-Ag-1/ GM-Tg-bovg-T60636-Ag-2 Bovine OGDH protein Bovine
GM-Tg-equg-T60636-Ag-1/ GM-Tg-equg-T60636-Ag-2 Equine OGDH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T60636-Ag-1/ GM-Tg-hg-T60636-Ag-2; GM-Tg-rg-T60636-Ag-1/ GM-Tg-rg-T60636-Ag-2;
GM-Tg-mg-T60636-Ag-1/ GM-Tg-mg-T60636-Ag-2; GM-Tg-cynog-T60636-Ag-1/ GM-Tg-cynog-T60636-Ag-2;
GM-Tg-felg-T60636-Ag-1/ GM-Tg-felg-T60636-Ag-2; GM-Tg-cang-T60636-Ag-1/ GM-Tg-cang-T60636-Ag-2;
GM-Tg-bovg-T60636-Ag-1/ GM-Tg-bovg-T60636-Ag-2; GM-Tg-equg-T60636-Ag-1/ GM-Tg-equg-T60636-Ag-2
Products Name OGDH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name OGDH
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OGDH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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