Recombinant multi-species COX-1/Cyclooxygenase-1/PTGS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX-1/Cyclooxygenase-1/PTGS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This is one of two genes encoding similar enzymes that catalyze the conversion of arachidonate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2021]
The Alternative Names of target: COX-1,COX-3,COX1,COX3,Cox-1,Cox-3,Cox1,Cox3,Cyclooxygenase-1,Cyclooxygenase-1 (COX-1),PCOX1,PES-1,PGG/HS,PGHS-1,PGHS1,PHS 1,PHS 1),PHS1,PTGHS,PTGS1,Pghs-1,Pghs1,Prostaglandin G/H synthase 1,Prostaglandin H2 synthase 1 (PGH synthase 1,Prostaglandin-endoperoxide synthase 1,Ptgs1

Target products collectionGo to COX-1/Cyclooxygenase-1/PTGS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T60529-Ag-1/ GM-Tg-hg-T60529-Ag-2 Human COX-1/Cyclooxygenase-1/PTGS1 protein Human
GM-Tg-rg-T60529-Ag-1/ GM-Tg-rg-T60529-Ag-2 Rat COX-1/Cyclooxygenase-1/PTGS1 protein Rat
GM-Tg-mg-T60529-Ag-1/ GM-Tg-mg-T60529-Ag-2 Mouse COX-1/Cyclooxygenase-1/PTGS1 protein Mouse
GM-Tg-cynog-T60529-Ag-1/ GM-Tg-cynog-T60529-Ag-2 Cynomolgus/Rhesus macaque COX-1/Cyclooxygenase-1/PTGS1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T60529-Ag-1/ GM-Tg-felg-T60529-Ag-2 Feline COX-1/Cyclooxygenase-1/PTGS1 protein Feline
GM-Tg-cang-T60529-Ag-1/ GM-Tg-cang-T60529-Ag-2 Canine COX-1/Cyclooxygenase-1/PTGS1 protein Canine
GM-Tg-bovg-T60529-Ag-1/ GM-Tg-bovg-T60529-Ag-2 Bovine COX-1/Cyclooxygenase-1/PTGS1 protein Bovine
GM-Tg-equg-T60529-Ag-1/ GM-Tg-equg-T60529-Ag-2 Equine COX-1/Cyclooxygenase-1/PTGS1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T60529-Ag-1/ GM-Tg-hg-T60529-Ag-2; GM-Tg-rg-T60529-Ag-1/ GM-Tg-rg-T60529-Ag-2;
GM-Tg-mg-T60529-Ag-1/ GM-Tg-mg-T60529-Ag-2; GM-Tg-cynog-T60529-Ag-1/ GM-Tg-cynog-T60529-Ag-2;
GM-Tg-felg-T60529-Ag-1/ GM-Tg-felg-T60529-Ag-2; GM-Tg-cang-T60529-Ag-1/ GM-Tg-cang-T60529-Ag-2;
GM-Tg-bovg-T60529-Ag-1/ GM-Tg-bovg-T60529-Ag-2; GM-Tg-equg-T60529-Ag-1/ GM-Tg-equg-T60529-Ag-2
Products Name COX-1/Cyclooxygenase-1/PTGS1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COX-1/Cyclooxygenase-1/PTGS1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX-1/Cyclooxygenase-1/PTGS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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