Recombinant multi-species CYP11B2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP11B2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ALDOS,Aldosterone synthase (ALDOS),Aldosterone-synthesizing enzyme,CPN2,CYP11B,CYP11B2,CYP11BL,CYPXIB2,Corticosterone 18-monooxygenase,Cpn2,Cyp11b,Cyp11b-2,Cyp11b2,Cytochrome P-450Aldo,Cytochrome P-450C18,Cytochrome P450 11B2,P-450C18,P450C18,P450aldo,Steroid 11-beta-hydroxylase,Steroid 18-hydroxylase,mitochondrial

Target products collectionGo to CYP11B2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T59056-Ag-1/ GM-Tg-hg-T59056-Ag-2 Human CYP11B2 protein Human
GM-Tg-rg-T59056-Ag-1/ GM-Tg-rg-T59056-Ag-2 Rat CYP11B2 protein Rat
GM-Tg-mg-T59056-Ag-1/ GM-Tg-mg-T59056-Ag-2 Mouse CYP11B2 protein Mouse
GM-Tg-cynog-T59056-Ag-1/ GM-Tg-cynog-T59056-Ag-2 Cynomolgus/Rhesus macaque CYP11B2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T59056-Ag-1/ GM-Tg-felg-T59056-Ag-2 Feline CYP11B2 protein Feline
GM-Tg-cang-T59056-Ag-1/ GM-Tg-cang-T59056-Ag-2 Canine CYP11B2 protein Canine
GM-Tg-bovg-T59056-Ag-1/ GM-Tg-bovg-T59056-Ag-2 Bovine CYP11B2 protein Bovine
GM-Tg-equg-T59056-Ag-1/ GM-Tg-equg-T59056-Ag-2 Equine CYP11B2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T59056-Ag-1/ GM-Tg-hg-T59056-Ag-2; GM-Tg-rg-T59056-Ag-1/ GM-Tg-rg-T59056-Ag-2;
GM-Tg-mg-T59056-Ag-1/ GM-Tg-mg-T59056-Ag-2; GM-Tg-cynog-T59056-Ag-1/ GM-Tg-cynog-T59056-Ag-2;
GM-Tg-felg-T59056-Ag-1/ GM-Tg-felg-T59056-Ag-2; GM-Tg-cang-T59056-Ag-1/ GM-Tg-cang-T59056-Ag-2;
GM-Tg-bovg-T59056-Ag-1/ GM-Tg-bovg-T59056-Ag-2; GM-Tg-equg-T59056-Ag-1/ GM-Tg-equg-T59056-Ag-2
Products Name CYP11B2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CYP11B2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP11B2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.