Recombinant multi-species PPAR Gamma/PPARG/PPAR-gamma protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPAR Gamma/PPARG/PPAR-gamma protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CIMT1,FPLD3,GLM1,NR1C3,Nr1c3,Nuclear receptor subfamily 1 group C member 3,PPAR Gamma,PPAR-GAMMA,PPAR-gamma,PPAR-gamma2,PPARG,PPARG1,PPARG2,PPARG5,PPARGAMMA,PPARgamma,PPARgamma2,Peroxisome proliferator-activated receptor gamma,Pparg

Target products collectionGo to PPAR Gamma/PPARG/PPAR-gamma products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T58921-Ag-1/ GM-Tg-hg-T58921-Ag-2 Human PPAR Gamma/PPARG/PPAR-gamma protein Human
GM-Tg-rg-T58921-Ag-1/ GM-Tg-rg-T58921-Ag-2 Rat PPAR Gamma/PPARG/PPAR-gamma protein Rat
GM-Tg-mg-T58921-Ag-1/ GM-Tg-mg-T58921-Ag-2 Mouse PPAR Gamma/PPARG/PPAR-gamma protein Mouse
GM-Tg-cynog-T58921-Ag-1/ GM-Tg-cynog-T58921-Ag-2 Cynomolgus/Rhesus macaque PPAR Gamma/PPARG/PPAR-gamma protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T58921-Ag-1/ GM-Tg-felg-T58921-Ag-2 Feline PPAR Gamma/PPARG/PPAR-gamma protein Feline
GM-Tg-cang-T58921-Ag-1/ GM-Tg-cang-T58921-Ag-2 Canine PPAR Gamma/PPARG/PPAR-gamma protein Canine
GM-Tg-bovg-T58921-Ag-1/ GM-Tg-bovg-T58921-Ag-2 Bovine PPAR Gamma/PPARG/PPAR-gamma protein Bovine
GM-Tg-equg-T58921-Ag-1/ GM-Tg-equg-T58921-Ag-2 Equine PPAR Gamma/PPARG/PPAR-gamma protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T58921-Ag-1/ GM-Tg-hg-T58921-Ag-2; GM-Tg-rg-T58921-Ag-1/ GM-Tg-rg-T58921-Ag-2;
GM-Tg-mg-T58921-Ag-1/ GM-Tg-mg-T58921-Ag-2; GM-Tg-cynog-T58921-Ag-1/ GM-Tg-cynog-T58921-Ag-2;
GM-Tg-felg-T58921-Ag-1/ GM-Tg-felg-T58921-Ag-2; GM-Tg-cang-T58921-Ag-1/ GM-Tg-cang-T58921-Ag-2;
GM-Tg-bovg-T58921-Ag-1/ GM-Tg-bovg-T58921-Ag-2; GM-Tg-equg-T58921-Ag-1/ GM-Tg-equg-T58921-Ag-2
Products Name PPAR Gamma/PPARG/PPAR-gamma protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPAR Gamma/PPARG/PPAR-gamma
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPAR Gamma/PPARG/PPAR-gamma protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.