Recombinant multi-species CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
The Alternative Names of target: A830040C14Rik,AC-3,Apopain,CASP-3,CASP3,CC3,CPP-32,CPP32,CPP32-beta,CPP32B,Casp3,Caspase 3,Caspase-3,Cleaved Caspase 3,Cysteine protease CPP32 (CPP-32),Lice,P17,P19,Protein Yama,SCA-1,SREBP cleavage activity 1 (SCA-1),Yama,mldy

Target products collectionGo to CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T57943-Ag-1/ GM-Tg-hg-T57943-Ag-2 Human CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Human
GM-Tg-rg-T57943-Ag-1/ GM-Tg-rg-T57943-Ag-2 Rat CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Rat
GM-Tg-mg-T57943-Ag-1/ GM-Tg-mg-T57943-Ag-2 Mouse CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Mouse
GM-Tg-cynog-T57943-Ag-1/ GM-Tg-cynog-T57943-Ag-2 Cynomolgus/Rhesus macaque CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T57943-Ag-1/ GM-Tg-felg-T57943-Ag-2 Feline CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Feline
GM-Tg-cang-T57943-Ag-1/ GM-Tg-cang-T57943-Ag-2 Canine CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Canine
GM-Tg-bovg-T57943-Ag-1/ GM-Tg-bovg-T57943-Ag-2 Bovine CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Bovine
GM-Tg-equg-T57943-Ag-1/ GM-Tg-equg-T57943-Ag-2 Equine CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T57943-Ag-1/ GM-Tg-hg-T57943-Ag-2; GM-Tg-rg-T57943-Ag-1/ GM-Tg-rg-T57943-Ag-2;
GM-Tg-mg-T57943-Ag-1/ GM-Tg-mg-T57943-Ag-2; GM-Tg-cynog-T57943-Ag-1/ GM-Tg-cynog-T57943-Ag-2;
GM-Tg-felg-T57943-Ag-1/ GM-Tg-felg-T57943-Ag-2; GM-Tg-cang-T57943-Ag-1/ GM-Tg-cang-T57943-Ag-2;
GM-Tg-bovg-T57943-Ag-1/ GM-Tg-bovg-T57943-Ag-2; GM-Tg-equg-T57943-Ag-1/ GM-Tg-equg-T57943-Ag-2
Products Name CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CASP3/Caspase 3/P17/P19/Cleaved Caspase 3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CASP3/Caspase 3/P17/P19/Cleaved Caspase 3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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