Recombinant multi-species TPP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
The Alternative Names of target: TPP1,Tripeptidyl-peptidase 1,TPP-1,Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease (LPIC), Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I (TPP-I),CLN2,GIG1,LPIC,SCAR7,TPP-1

Target products collectionGo to TPP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T56262-Ab-1/ GM-Tg-hg-T56262-Ab-2 Human TPP1 protein Human
GM-Tg-rg-T56262-Ab-1/ GM-Tg-rg-T56262-Ab-2 Rat TPP1 protein Rat
GM-Tg-mg-T56262-Ab-1/ GM-Tg-mg-T56262-Ab-2 Mouse TPP1 protein Mouse
GM-Tg-cynog-T56262-Ab-1/ GM-Tg-cynog-T56262-Ab-2 Cynomolgus/Rhesus macaque TPP1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T56262-Ab-1/ GM-Tg-felg-T56262-Ab-2 Feline TPP1 protein Feline
GM-Tg-cang-T56262-Ab-1/ GM-Tg-cang-T56262-Ab-2 Canine TPP1 protein Canine
GM-Tg-bovg-T56262-Ab-1/ GM-Tg-bovg-T56262-Ab-2 Bovine TPP1 protein Bovine
GM-Tg-equg-T56262-Ab-1/ GM-Tg-equg-T56262-Ab-2 Equine TPP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T56262-Ab-1/ GM-Tg-hg-T56262-Ab-2; GM-Tg-rg-T56262-Ab-1/ GM-Tg-rg-T56262-Ab-2;
GM-Tg-mg-T56262-Ab-1/ GM-Tg-mg-T56262-Ab-2; GM-Tg-cynog-T56262-Ab-1/ GM-Tg-cynog-T56262-Ab-2;
GM-Tg-felg-T56262-Ab-1/ GM-Tg-felg-T56262-Ab-2; GM-Tg-cang-T56262-Ab-1/ GM-Tg-cang-T56262-Ab-2;
GM-Tg-bovg-T56262-Ab-1/ GM-Tg-bovg-T56262-Ab-2; GM-Tg-equg-T56262-Ab-1/ GM-Tg-equg-T56262-Ab-2
Products Name TPP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPP1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.