Recombinant multi-species IRAK4/IRAK-4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRAK4/IRAK-4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
The Alternative Names of target: IRAK4, IRAK-4,Interleukin-1 receptor-associated kinase 4,IRAK-4,Renal carcinoma antigen NY-REN-64,IPD1,IMD67,REN64,IRAK-4,NY-REN-64

Target products collectionGo to IRAK4/IRAK-4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T55398-Ab-1/ GM-Tg-hg-T55398-Ab-2 Human IRAK4/IRAK-4 protein Human
GM-Tg-rg-T55398-Ab-1/ GM-Tg-rg-T55398-Ab-2 Rat IRAK4/IRAK-4 protein Rat
GM-Tg-mg-T55398-Ab-1/ GM-Tg-mg-T55398-Ab-2 Mouse IRAK4/IRAK-4 protein Mouse
GM-Tg-cynog-T55398-Ab-1/ GM-Tg-cynog-T55398-Ab-2 Cynomolgus/Rhesus macaque IRAK4/IRAK-4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T55398-Ab-1/ GM-Tg-felg-T55398-Ab-2 Feline IRAK4/IRAK-4 protein Feline
GM-Tg-cang-T55398-Ab-1/ GM-Tg-cang-T55398-Ab-2 Canine IRAK4/IRAK-4 protein Canine
GM-Tg-bovg-T55398-Ab-1/ GM-Tg-bovg-T55398-Ab-2 Bovine IRAK4/IRAK-4 protein Bovine
GM-Tg-equg-T55398-Ab-1/ GM-Tg-equg-T55398-Ab-2 Equine IRAK4/IRAK-4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T55398-Ab-1/ GM-Tg-hg-T55398-Ab-2; GM-Tg-rg-T55398-Ab-1/ GM-Tg-rg-T55398-Ab-2;
GM-Tg-mg-T55398-Ab-1/ GM-Tg-mg-T55398-Ab-2; GM-Tg-cynog-T55398-Ab-1/ GM-Tg-cynog-T55398-Ab-2;
GM-Tg-felg-T55398-Ab-1/ GM-Tg-felg-T55398-Ab-2; GM-Tg-cang-T55398-Ab-1/ GM-Tg-cang-T55398-Ab-2;
GM-Tg-bovg-T55398-Ab-1/ GM-Tg-bovg-T55398-Ab-2; GM-Tg-equg-T55398-Ab-1/ GM-Tg-equg-T55398-Ab-2
Products Name IRAK4/IRAK-4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IRAK4/IRAK-4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IRAK4/IRAK-4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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