Recombinant multi-species BNP/NPPB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNP/NPPB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020]
The Alternative Names of target: BNF,BNP,Bnf,Brain natriuretic factor prohormone (preproBNP,Gamma-brain natriuretic peptide,Iso-ANP,NNX,NPPB,Natriuretic peptides B,Nppb,proBNP)

Target products collectionGo to BNP/NPPB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T55302-Ag-1/ GM-Tg-hg-T55302-Ag-2 Human BNP/NPPB protein Human
GM-Tg-rg-T55302-Ag-1/ GM-Tg-rg-T55302-Ag-2 Rat BNP/NPPB protein Rat
GM-Tg-mg-T55302-Ag-1/ GM-Tg-mg-T55302-Ag-2 Mouse BNP/NPPB protein Mouse
GM-Tg-cynog-T55302-Ag-1/ GM-Tg-cynog-T55302-Ag-2 Cynomolgus/Rhesus macaque BNP/NPPB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T55302-Ag-1/ GM-Tg-felg-T55302-Ag-2 Feline BNP/NPPB protein Feline
GM-Tg-cang-T55302-Ag-1/ GM-Tg-cang-T55302-Ag-2 Canine BNP/NPPB protein Canine
GM-Tg-bovg-T55302-Ag-1/ GM-Tg-bovg-T55302-Ag-2 Bovine BNP/NPPB protein Bovine
GM-Tg-equg-T55302-Ag-1/ GM-Tg-equg-T55302-Ag-2 Equine BNP/NPPB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T55302-Ag-1/ GM-Tg-hg-T55302-Ag-2; GM-Tg-rg-T55302-Ag-1/ GM-Tg-rg-T55302-Ag-2;
GM-Tg-mg-T55302-Ag-1/ GM-Tg-mg-T55302-Ag-2; GM-Tg-cynog-T55302-Ag-1/ GM-Tg-cynog-T55302-Ag-2;
GM-Tg-felg-T55302-Ag-1/ GM-Tg-felg-T55302-Ag-2; GM-Tg-cang-T55302-Ag-1/ GM-Tg-cang-T55302-Ag-2;
GM-Tg-bovg-T55302-Ag-1/ GM-Tg-bovg-T55302-Ag-2; GM-Tg-equg-T55302-Ag-1/ GM-Tg-equg-T55302-Ag-2
Products Name BNP/NPPB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BNP/NPPB
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BNP/NPPB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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