Recombinant multi-species MMP-9/MMP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP-9/MMP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 92 kDa gelatinase,92 kDa type IV collagenase,B/MMP9,CLG4B,Clg4b,GELB,Gel B,Gelatinase B (GELB),MANDP2,MMP-9,MMP9,Matrix metalloproteinase-9,Mmp9,pro-MMP-9

Target products collectionGo to MMP-9/MMP9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T54156-Ag-1/ GM-Tg-hg-T54156-Ag-2 Human MMP-9/MMP9 protein Human
GM-Tg-rg-T54156-Ag-1/ GM-Tg-rg-T54156-Ag-2 Rat MMP-9/MMP9 protein Rat
GM-Tg-mg-T54156-Ag-1/ GM-Tg-mg-T54156-Ag-2 Mouse MMP-9/MMP9 protein Mouse
GM-Tg-cynog-T54156-Ag-1/ GM-Tg-cynog-T54156-Ag-2 Cynomolgus/Rhesus macaque MMP-9/MMP9 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T54156-Ag-1/ GM-Tg-felg-T54156-Ag-2 Feline MMP-9/MMP9 protein Feline
GM-Tg-cang-T54156-Ag-1/ GM-Tg-cang-T54156-Ag-2 Canine MMP-9/MMP9 protein Canine
GM-Tg-bovg-T54156-Ag-1/ GM-Tg-bovg-T54156-Ag-2 Bovine MMP-9/MMP9 protein Bovine
GM-Tg-equg-T54156-Ag-1/ GM-Tg-equg-T54156-Ag-2 Equine MMP-9/MMP9 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T54156-Ag-1/ GM-Tg-hg-T54156-Ag-2; GM-Tg-rg-T54156-Ag-1/ GM-Tg-rg-T54156-Ag-2;
GM-Tg-mg-T54156-Ag-1/ GM-Tg-mg-T54156-Ag-2; GM-Tg-cynog-T54156-Ag-1/ GM-Tg-cynog-T54156-Ag-2;
GM-Tg-felg-T54156-Ag-1/ GM-Tg-felg-T54156-Ag-2; GM-Tg-cang-T54156-Ag-1/ GM-Tg-cang-T54156-Ag-2;
GM-Tg-bovg-T54156-Ag-1/ GM-Tg-bovg-T54156-Ag-2; GM-Tg-equg-T54156-Ag-1/ GM-Tg-equg-T54156-Ag-2
Products Name MMP-9/MMP9 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMP-9/MMP9
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP-9/MMP9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.