Recombinant multi-species MMP-9/MMP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP-9/MMP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 92 kDa gelatinase,92 kDa type IV collagenase,B/MMP9,CLG4B,Clg4b,GELB,Gel B,Gelatinase B (GELB),MANDP2,MMP-9,MMP9,Matrix metalloproteinase-9,Mmp9,pro-MMP-9
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T54156-Ag-1/ GM-Tg-hg-T54156-Ag-2 | Human MMP-9/MMP9 protein | Human |
GM-Tg-rg-T54156-Ag-1/ GM-Tg-rg-T54156-Ag-2 | Rat MMP-9/MMP9 protein | Rat |
GM-Tg-mg-T54156-Ag-1/ GM-Tg-mg-T54156-Ag-2 | Mouse MMP-9/MMP9 protein | Mouse |
GM-Tg-cynog-T54156-Ag-1/ GM-Tg-cynog-T54156-Ag-2 | Cynomolgus/Rhesus macaque MMP-9/MMP9 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T54156-Ag-1/ GM-Tg-felg-T54156-Ag-2 | Feline MMP-9/MMP9 protein | Feline |
GM-Tg-cang-T54156-Ag-1/ GM-Tg-cang-T54156-Ag-2 | Canine MMP-9/MMP9 protein | Canine |
GM-Tg-bovg-T54156-Ag-1/ GM-Tg-bovg-T54156-Ag-2 | Bovine MMP-9/MMP9 protein | Bovine |
GM-Tg-equg-T54156-Ag-1/ GM-Tg-equg-T54156-Ag-2 | Equine MMP-9/MMP9 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T54156-Ag-1/ GM-Tg-hg-T54156-Ag-2;
GM-Tg-rg-T54156-Ag-1/ GM-Tg-rg-T54156-Ag-2;
GM-Tg-mg-T54156-Ag-1/ GM-Tg-mg-T54156-Ag-2; GM-Tg-cynog-T54156-Ag-1/ GM-Tg-cynog-T54156-Ag-2; GM-Tg-felg-T54156-Ag-1/ GM-Tg-felg-T54156-Ag-2; GM-Tg-cang-T54156-Ag-1/ GM-Tg-cang-T54156-Ag-2; GM-Tg-bovg-T54156-Ag-1/ GM-Tg-bovg-T54156-Ag-2; GM-Tg-equg-T54156-Ag-1/ GM-Tg-equg-T54156-Ag-2 |
Products Name | MMP-9/MMP9 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | MMP-9/MMP9 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP-9/MMP9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.