Explore MMP-9/MMP9 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Target ID |
GM-T54156
|
Target Name |
MMP-9/MMP9
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4318
|
Gene ID |
100056599 (Equus caballus), 101084185 (Felis catus), 17395 (Mus musculus), 282871 (Bos taurus) 403885 (Canis lupus familiaris), 4318 (Homo sapiens), 708084 (Macaca mulatta), 81687 (Rattus norvegicus)
|
Target Alternative Names |
92 kDa gelatinase,92 kDa type IV collagenase,B/MMP9,CLG4B,Clg4b,GELB,Gel B,Gelatinase B (GELB),MANDP2,MMP-9,MMP9,Matrix metalloproteinase-9,Mmp9,pro-MMP-9
|
Uniprot Accession |
P41245,P52176,O18733,P14780,P50282
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
Therapeutics Target, INN Index
|
Disease |
cancer, Breast Cancer, Breast Cancer, Malignant neoplasm of bladder, Renal cell carcinoma, Neoplasm, Hemangioma, Malignant neoplasms of female genital organs, Alport syndrome, Calculus of kidney, Chronic Kidney Disease, Chronic tubulo-interstitial nephritis, Congenital occlusion of ureteropelvic junction
|
Disease from KEGG |
Endocrine resistance, IL-17 signaling pathway, TNF signaling pathway, Leukocyte transendothelial migration, Relaxin signaling pathway, Hepatitis B, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
Gene Ensembl |
ENSECAG00000013081, ENSMUSG00000017737, ENSBTAG00000020676, ENSCAFG00845017615, ENSG00000100985, ENSMMUG00000016549
|
Target Classification |
|
Pre-made viral vector of MMP-9/MMP9 cDNA Clones/ORF Plasmid
MMP-9/MMP9 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo4318 | Pre-made Human MMP9/GELB/CLG4B siRNA oligo Duplex | 4318 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo81687 | Pre-made Rat Mmp9 siRNA oligo Duplex | 81687 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo17395 | Pre-made Mouse Mmp9/Clg4b/Gel B siRNA oligo Duplex | 17395 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo708084 | Pre-made Cynomolgus/Rhesus macaque MMP9 siRNA oligo Duplex | 708084 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101084185 | Pre-made Cat/Feline MMP9/MMP-9 siRNA oligo Duplex | 101084185 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo403885 | Pre-made Dog/Canine MMP9 siRNA oligo Duplex | 403885 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo282871 | Pre-made Bovines/Cattle MMP9 siRNA oligo Duplex | 282871 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100056599 | Pre-made Equine/Horse MMP9 siRNA oligo Duplex | 100056599 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MMP-9/MMP9 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T54156-Ab | Human | Anti-Human MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-T54156-Ab | Rat | Anti-Rat MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-T54156-Ab | Mouse | Anti-Mouse MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T54156-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-T54156-Ab | Cat/Feline | Anti-Cat/Feline MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-T54156-Ab | Dog/Canine | Anti-Dog/Canine MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T54156-Ab | Bovines/Cattle | Anti-Bovines/Cattle MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T54156-Ab | Equine/Horse | Anti-Equine/Horse MMP-9/MMP9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MMP-9/MMP9 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T54156-Ag | Human | Human MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T54156-Ag | Rat | Rat MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T54156-Ag | Mouse | Mouse MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T54156-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T54156-Ag | Cat/Feline | Cat/Feline MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T54156-Ag | Dog/Canine | Dog/Canine MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T54156-Ag | Bovines/Cattle | Bovines/Cattle MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T54156-Ag | Equine/Horse | Equine/Horse MMP-9/MMP9 recombinant protein | Mammalian cell | Detail |