Recombinant multi-species KLK6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
The Alternative Names of target: Bssp,KLK6,KLNI,Kallikrein-6,Klk6,Klk7,Klni,Neurosin,PRSS18,PRSS9,Protease M,Prss9,SP59,Serine protease 18,Serine protease 9,Zyme,hK6

Target products collectionGo to KLK6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T53612-Ag-1/ GM-Tg-hg-T53612-Ag-2 Human KLK6 protein Human
GM-Tg-rg-T53612-Ag-1/ GM-Tg-rg-T53612-Ag-2 Rat KLK6 protein Rat
GM-Tg-mg-T53612-Ag-1/ GM-Tg-mg-T53612-Ag-2 Mouse KLK6 protein Mouse
GM-Tg-cynog-T53612-Ag-1/ GM-Tg-cynog-T53612-Ag-2 Cynomolgus/Rhesus macaque KLK6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T53612-Ag-1/ GM-Tg-felg-T53612-Ag-2 Feline KLK6 protein Feline
GM-Tg-cang-T53612-Ag-1/ GM-Tg-cang-T53612-Ag-2 Canine KLK6 protein Canine
GM-Tg-bovg-T53612-Ag-1/ GM-Tg-bovg-T53612-Ag-2 Bovine KLK6 protein Bovine
GM-Tg-equg-T53612-Ag-1/ GM-Tg-equg-T53612-Ag-2 Equine KLK6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T53612-Ag-1/ GM-Tg-hg-T53612-Ag-2; GM-Tg-rg-T53612-Ag-1/ GM-Tg-rg-T53612-Ag-2;
GM-Tg-mg-T53612-Ag-1/ GM-Tg-mg-T53612-Ag-2; GM-Tg-cynog-T53612-Ag-1/ GM-Tg-cynog-T53612-Ag-2;
GM-Tg-felg-T53612-Ag-1/ GM-Tg-felg-T53612-Ag-2; GM-Tg-cang-T53612-Ag-1/ GM-Tg-cang-T53612-Ag-2;
GM-Tg-bovg-T53612-Ag-1/ GM-Tg-bovg-T53612-Ag-2; GM-Tg-equg-T53612-Ag-1/ GM-Tg-equg-T53612-Ag-2
Products Name KLK6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KLK6
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KLK6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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