Recombinant multi-species XRCC5/Ku80 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XRCC5/Ku80 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.  This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit (CTC85,CTC85,CTCBF,CTCBF),DNA repair protein XRCC5,KARP-1,KARP1,KU80,KUB2,Ku80,Ku86,Kup80,Lupus Ku autoantigen protein p86,NFIV,Nuclear factor IV,Thyroid-lupus autoantigen (TLAA),X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining),X-ray repair cross-complementing protein 5,XRCC5,Xrcc5

Target products collectionGo to XRCC5/Ku80 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T53562-Ag-1/ GM-Tg-hg-T53562-Ag-2 Human XRCC5/Ku80 protein Human
GM-Tg-rg-T53562-Ag-1/ GM-Tg-rg-T53562-Ag-2 Rat XRCC5/Ku80 protein Rat
GM-Tg-mg-T53562-Ag-1/ GM-Tg-mg-T53562-Ag-2 Mouse XRCC5/Ku80 protein Mouse
GM-Tg-cynog-T53562-Ag-1/ GM-Tg-cynog-T53562-Ag-2 Cynomolgus/Rhesus macaque XRCC5/Ku80 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T53562-Ag-1/ GM-Tg-felg-T53562-Ag-2 Feline XRCC5/Ku80 protein Feline
GM-Tg-cang-T53562-Ag-1/ GM-Tg-cang-T53562-Ag-2 Canine XRCC5/Ku80 protein Canine
GM-Tg-bovg-T53562-Ag-1/ GM-Tg-bovg-T53562-Ag-2 Bovine XRCC5/Ku80 protein Bovine
GM-Tg-equg-T53562-Ag-1/ GM-Tg-equg-T53562-Ag-2 Equine XRCC5/Ku80 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T53562-Ag-1/ GM-Tg-hg-T53562-Ag-2; GM-Tg-rg-T53562-Ag-1/ GM-Tg-rg-T53562-Ag-2;
GM-Tg-mg-T53562-Ag-1/ GM-Tg-mg-T53562-Ag-2; GM-Tg-cynog-T53562-Ag-1/ GM-Tg-cynog-T53562-Ag-2;
GM-Tg-felg-T53562-Ag-1/ GM-Tg-felg-T53562-Ag-2; GM-Tg-cang-T53562-Ag-1/ GM-Tg-cang-T53562-Ag-2;
GM-Tg-bovg-T53562-Ag-1/ GM-Tg-bovg-T53562-Ag-2; GM-Tg-equg-T53562-Ag-1/ GM-Tg-equg-T53562-Ag-2
Products Name XRCC5/Ku80 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name XRCC5/Ku80
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine XRCC5/Ku80 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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