Recombinant multi-species WNK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]
The Alternative Names of target: 6430573H23Rik,EG406236,Erythrocyte 65 kDa protein (p65),HSAN2,HSN2,Hsn2,KDP,Kinase deficient protein,PPP1R167,PRKWNK1,PSK,Prkwnk1,Protein kinase lysine-deficient 1,Protein kinase with no lysine 1 (hWNK1),Serine/threonine-protein kinase WNK1,WNK1,Wnk1,mKIAA0344,p65

Target products collectionGo to WNK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T52638-Ag-1/ GM-Tg-hg-T52638-Ag-2 Human WNK1 protein Human
GM-Tg-rg-T52638-Ag-1/ GM-Tg-rg-T52638-Ag-2 Rat WNK1 protein Rat
GM-Tg-mg-T52638-Ag-1/ GM-Tg-mg-T52638-Ag-2 Mouse WNK1 protein Mouse
GM-Tg-cynog-T52638-Ag-1/ GM-Tg-cynog-T52638-Ag-2 Cynomolgus/Rhesus macaque WNK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T52638-Ag-1/ GM-Tg-felg-T52638-Ag-2 Feline WNK1 protein Feline
GM-Tg-cang-T52638-Ag-1/ GM-Tg-cang-T52638-Ag-2 Canine WNK1 protein Canine
GM-Tg-bovg-T52638-Ag-1/ GM-Tg-bovg-T52638-Ag-2 Bovine WNK1 protein Bovine
GM-Tg-equg-T52638-Ag-1/ GM-Tg-equg-T52638-Ag-2 Equine WNK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T52638-Ag-1/ GM-Tg-hg-T52638-Ag-2; GM-Tg-rg-T52638-Ag-1/ GM-Tg-rg-T52638-Ag-2;
GM-Tg-mg-T52638-Ag-1/ GM-Tg-mg-T52638-Ag-2; GM-Tg-cynog-T52638-Ag-1/ GM-Tg-cynog-T52638-Ag-2;
GM-Tg-felg-T52638-Ag-1/ GM-Tg-felg-T52638-Ag-2; GM-Tg-cang-T52638-Ag-1/ GM-Tg-cang-T52638-Ag-2;
GM-Tg-bovg-T52638-Ag-1/ GM-Tg-bovg-T52638-Ag-2; GM-Tg-equg-T52638-Ag-1/ GM-Tg-equg-T52638-Ag-2
Products Name WNK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WNK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WNK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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