Explore WNK1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]
| Target ID |
GM-T52638
|
| Target Name |
WNK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
65125
|
| Gene ID |
100056745 (Equus caballus), 101096818 (Felis catus), 116477 (Rattus norvegicus), 232341 (Mus musculus)
477728 (Canis lupus familiaris), 506433 (Bos taurus), 65125 (Homo sapiens), 706493 (Macaca mulatta)
|
| Target Alternative Names |
6430573H23Rik,EG406236,Erythrocyte 65 kDa protein (p65),HSAN2,HSN2,Hsn2,KDP,Kinase deficient protein,PPP1R167,PRKWNK1,PSK,Prkwnk1,Protein kinase lysine-deficient 1,Protein kinase with no lysine 1 (hWNK1),Serine/threonine-protein kinase WNK1,WNK1,Wnk1,mKIAA0344,p65
|
| Uniprot Accession |
Q9JIH7,P83741,Q9H4A3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000023501, ENSMUSG00000045962, ENSCAFG00845028333, ENSBTAG00000005221, ENSG00000060237, ENSMMUG00000018650
|
WNK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo65125 | Pre-made Human WNK1/KDP/PSK siRNA oligo Duplex | 65125 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116477 | Pre-made Rat Wnk1/Hsn2/Prkwnk1 siRNA oligo Duplex | 116477 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo232341 | Pre-made Mouse Wnk1/Hsn2/Prkwnk1 siRNA oligo Duplex | 232341 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706493 | Pre-made Cynomolgus/Rhesus macaque WNK1/HSN2 siRNA oligo Duplex | 706493 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096818 | Pre-made Cat/Feline WNK1 siRNA oligo Duplex | 101096818 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477728 | Pre-made Dog/Canine WNK1 siRNA oligo Duplex | 477728 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506433 | Pre-made Bovines/Cattle WNK1 siRNA oligo Duplex | 506433 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056745 | Pre-made Equine/Horse WNK1/HSN2 siRNA oligo Duplex | 100056745 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
WNK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52638-Ab | Human | Anti-Human WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52638-Ab | Rat | Anti-Rat WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52638-Ab | Mouse | Anti-Mouse WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52638-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52638-Ab | Cat/Feline | Anti-Cat/Feline WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52638-Ab | Dog/Canine | Anti-Dog/Canine WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52638-Ab | Bovines/Cattle | Anti-Bovines/Cattle WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52638-Ab | Equine/Horse | Anti-Equine/Horse WNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
WNK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52638-Ag | Human | Human WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T52638-Ag | Rat | Rat WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T52638-Ag | Mouse | Mouse WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T52638-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T52638-Ag | Cat/Feline | Cat/Feline WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T52638-Ag | Dog/Canine | Dog/Canine WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T52638-Ag | Bovines/Cattle | Bovines/Cattle WNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T52638-Ag | Equine/Horse | Equine/Horse WNK1 recombinant protein | Mammalian cell | Detail |
