Recombinant multi-species NQO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NQO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Azoreductase,DHQU,DIA4,DT-diaphorase (DTD),DTD,Dia4,Dtd,Menadione reductase,NAD(P)H dehydrogenase [quinone] 1,NAD(P)H:quinone oxidoreductase 1,NMOR1,NMORI,NQO1,Nmo-1,Nmo1,Nmor1,Nqo1,Ox-1,Ox1,Phylloquinone reductase,QR1,Qr1,Quinone reductase 1 (QR1)

Target products collectionGo to NQO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T52389-Ag-1/ GM-Tg-hg-T52389-Ag-2 Human NQO1 protein Human
GM-Tg-rg-T52389-Ag-1/ GM-Tg-rg-T52389-Ag-2 Rat NQO1 protein Rat
GM-Tg-mg-T52389-Ag-1/ GM-Tg-mg-T52389-Ag-2 Mouse NQO1 protein Mouse
GM-Tg-cynog-T52389-Ag-1/ GM-Tg-cynog-T52389-Ag-2 Cynomolgus/Rhesus macaque NQO1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T52389-Ag-1/ GM-Tg-felg-T52389-Ag-2 Feline NQO1 protein Feline
GM-Tg-cang-T52389-Ag-1/ GM-Tg-cang-T52389-Ag-2 Canine NQO1 protein Canine
GM-Tg-bovg-T52389-Ag-1/ GM-Tg-bovg-T52389-Ag-2 Bovine NQO1 protein Bovine
GM-Tg-equg-T52389-Ag-1/ GM-Tg-equg-T52389-Ag-2 Equine NQO1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T52389-Ag-1/ GM-Tg-hg-T52389-Ag-2; GM-Tg-rg-T52389-Ag-1/ GM-Tg-rg-T52389-Ag-2;
GM-Tg-mg-T52389-Ag-1/ GM-Tg-mg-T52389-Ag-2; GM-Tg-cynog-T52389-Ag-1/ GM-Tg-cynog-T52389-Ag-2;
GM-Tg-felg-T52389-Ag-1/ GM-Tg-felg-T52389-Ag-2; GM-Tg-cang-T52389-Ag-1/ GM-Tg-cang-T52389-Ag-2;
GM-Tg-bovg-T52389-Ag-1/ GM-Tg-bovg-T52389-Ag-2; GM-Tg-equg-T52389-Ag-1/ GM-Tg-equg-T52389-Ag-2
Products Name NQO1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NQO1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NQO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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