NQO1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore NQO1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Target ID GM-T52389
Target Name NQO1
Gene Group ldentifer
(Target Gene ID in Homo species)
1728
Gene ID 100067237 (Equus caballus), 101097859 (Felis catus), 1728 (Homo sapiens), 18104 (Mus musculus)
24314 (Rattus norvegicus), 519632 (Bos taurus), 610935 (Canis lupus familiaris), 705635 (Macaca mulatta)
Target Alternative Names Azoreductase,DHQU,DIA4,DT-diaphorase (DTD),DTD,Dia4,Dtd,Menadione reductase,NAD(P)H dehydrogenase [quinone] 1,NAD(P)H:quinone oxidoreductase 1,NMOR1,NMORI,NQO1,Nmo-1,Nmo1,Nmor1,Nqo1,Ox-1,Ox1,Phylloquinone reductase,QR1,Qr1,Quinone reductase 1 (QR1)
Uniprot Accession P15559,Q64669,P05982
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Metabolic pathways, Pathways in cancer, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis
Gene Ensembl ENSECAG00000020378, ENSG00000181019, ENSMUSG00000003849, ENSBTAG00000020632, ENSCAFG00845009149, ENSMMUG00000019684
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of NQO1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP000898Human NQO1/DHQU/DIA4 Lentivirus plasmidNM_0009031728HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000811Human NQO1/DHQU/DIA4 Lentivirus plasmidNM_0009031728HumanLentivirus plasmidZsGreenNullCMVDetail
vGMLP000898Human NQO1/DHQU/DIA4 Lentivirus particleNM_0009031728HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000811Human NQO1/DHQU/DIA4 Lentivirus particleNM_0009031728HumanLentivirus particleZsGreenNullCMVDetail
pGMAAV000479Mouse Nqo1/AV001255/Dia4 Adeno-associate virus(AAV) plasmidNM_008706.518104MouseAdeno-associate virus(AAV) plasmidFirefly luciferaseNullCMVDetail
pGMLPm000830Mouse Nqo1/AV001255/Dia4 Lentivirus plasmidNM_00870618104MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000479Mouse Nqo1/AV001255/Dia4 Adeno-associate virus(AAV) particleNM_008706.518104MouseAdeno-associate virus(AAV) particleFirefly luciferaseNullCMVDetail
vGMLPm000830Mouse Nqo1/AV001255/Dia4 Lentivirus particleNM_00870618104MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


NQO1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo1728Pre-made Human NQO1/DTD/QR1 siRNA oligo Duplex1728HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24314Pre-made Rat Nqo1/Dia4 siRNA oligo Duplex24314RatIn-vitro grade; in-vivo gradeDetail
pGMoligo18104Pre-made Mouse Nqo1/Dtd/Ox1 siRNA oligo Duplex18104MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo705635Pre-made Cynomolgus/Rhesus macaque NQO1 siRNA oligo Duplex705635Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101097859Pre-made Cat/Feline NQO1 siRNA oligo Duplex101097859Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo610935Pre-made Dog/Canine NQO1 siRNA oligo Duplex610935Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo519632Pre-made Bovines/Cattle NQO1/DIA4 siRNA oligo Duplex519632Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100067237Pre-made Equine/Horse NQO1 siRNA oligo Duplex100067237Equine/HorseIn-vitro grade; in-vivo gradeDetail


NQO1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T52389-AbHumanAnti-Human NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T52389-AbRatAnti-Rat NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T52389-AbMouseAnti-Mouse NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T52389-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T52389-AbCat/FelineAnti-Cat/Feline NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T52389-AbDog/CanineAnti-Dog/Canine NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T52389-AbBovines/CattleAnti-Bovines/Cattle NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T52389-AbEquine/HorseAnti-Equine/Horse NQO1 monoclonal antibodymabTherapeutics Target antibodyDetail


NQO1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T52389-AgHumanHuman NQO1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T52389-AgRatRat NQO1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T52389-AgMouseMouse NQO1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T52389-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque NQO1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T52389-AgCat/FelineCat/Feline NQO1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T52389-AgDog/CanineDog/Canine NQO1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T52389-AgBovines/CattleBovines/Cattle NQO1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T52389-AgEquine/HorseEquine/Horse NQO1 recombinant proteinMammalian cellDetail