Recombinant multi-species LBP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LBP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
The Alternative Names of target: BPIFD2,Bpifd2,LBP,Lbp,Lipopolysaccharide-binding protein,Ly88

Target products collectionGo to LBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T52110-Ag-1/ GM-Tg-hg-T52110-Ag-2 Human LBP protein Human
GM-Tg-rg-T52110-Ag-1/ GM-Tg-rg-T52110-Ag-2 Rat LBP protein Rat
GM-Tg-mg-T52110-Ag-1/ GM-Tg-mg-T52110-Ag-2 Mouse LBP protein Mouse
GM-Tg-cynog-T52110-Ag-1/ GM-Tg-cynog-T52110-Ag-2 Cynomolgus/Rhesus macaque LBP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T52110-Ag-1/ GM-Tg-felg-T52110-Ag-2 Feline LBP protein Feline
GM-Tg-cang-T52110-Ag-1/ GM-Tg-cang-T52110-Ag-2 Canine LBP protein Canine
GM-Tg-bovg-T52110-Ag-1/ GM-Tg-bovg-T52110-Ag-2 Bovine LBP protein Bovine
GM-Tg-equg-T52110-Ag-1/ GM-Tg-equg-T52110-Ag-2 Equine LBP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T52110-Ag-1/ GM-Tg-hg-T52110-Ag-2; GM-Tg-rg-T52110-Ag-1/ GM-Tg-rg-T52110-Ag-2;
GM-Tg-mg-T52110-Ag-1/ GM-Tg-mg-T52110-Ag-2; GM-Tg-cynog-T52110-Ag-1/ GM-Tg-cynog-T52110-Ag-2;
GM-Tg-felg-T52110-Ag-1/ GM-Tg-felg-T52110-Ag-2; GM-Tg-cang-T52110-Ag-1/ GM-Tg-cang-T52110-Ag-2;
GM-Tg-bovg-T52110-Ag-1/ GM-Tg-bovg-T52110-Ag-2; GM-Tg-equg-T52110-Ag-1/ GM-Tg-equg-T52110-Ag-2
Products Name LBP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LBP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LBP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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