Explore LBP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
| Target ID |
GM-T52110
|
| Target Name |
LBP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3929
|
| Gene ID |
100070103 (Equus caballus), 16803 (Mus musculus), 29469 (Rattus norvegicus), 3929 (Homo sapiens) 485869 (Canis lupus familiaris), 512242 (Bos taurus), 706109 (Macaca mulatta)
|
| Target Alternative Names |
BPIFD2,Bpifd2,LBP,Lbp,Lipopolysaccharide-binding protein,Ly88
|
| Uniprot Accession |
Q61805,Q63313,P18428,Q2TBI0
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
Breast Cancer, Sepsis
|
| Disease from KEGG |
NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Alcoholic liver disease, Tuberculosis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSMUSG00000016024, ENSG00000129988, ENSCAFG00845029162, ENSBTAG00000016864, ENSMMUG00000007563
|
Pre-made viral vector of LBP cDNA Clones/ORF Plasmid
LBP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3929 | Pre-made Human LBP/BPIFD2 siRNA oligo Duplex | 3929 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29469 | Pre-made Rat Lbp/Bpifd2 siRNA oligo Duplex | 29469 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16803 | Pre-made Mouse Lbp/Ly88/Bpifd2 siRNA oligo Duplex | 16803 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706109 | Pre-made Cynomolgus/Rhesus macaque LBP siRNA oligo Duplex | 706109 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485869 | Pre-made Dog/Canine LBP siRNA oligo Duplex | 485869 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512242 | Pre-made Bovines/Cattle LBP siRNA oligo Duplex | 512242 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070103 | Pre-made Equine/Horse LBP siRNA oligo Duplex | 100070103 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LBP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52110-Ab | Human | Anti-Human LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52110-Ab | Rat | Anti-Rat LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52110-Ab | Mouse | Anti-Mouse LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52110-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52110-Ab | Dog/Canine | Anti-Dog/Canine LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52110-Ab | Bovines/Cattle | Anti-Bovines/Cattle LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52110-Ab | Equine/Horse | Anti-Equine/Horse LBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LBP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52110-Ag | Human | Human LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T52110-Ag | Rat | Rat LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T52110-Ag | Mouse | Mouse LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T52110-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T52110-Ag | Dog/Canine | Dog/Canine LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T52110-Ag | Bovines/Cattle | Bovines/Cattle LBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T52110-Ag | Equine/Horse | Equine/Horse LBP recombinant protein | Mammalian cell | Detail |