Recombinant multi-species GM2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GM2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
The Alternative Names of target: Cerebroside sulfate activator protein,GM2-AP,GM2A,GM2AP,Ganglioside GM2 activator,Gm2a,SAP-3,Sphingolipid activator protein 3 (SAP-3)

Target products collectionGo to GM2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T51499-Ag-1/ GM-Tg-hg-T51499-Ag-2 Human GM2A protein Human
GM-Tg-rg-T51499-Ag-1/ GM-Tg-rg-T51499-Ag-2 Rat GM2A protein Rat
GM-Tg-mg-T51499-Ag-1/ GM-Tg-mg-T51499-Ag-2 Mouse GM2A protein Mouse
GM-Tg-cynog-T51499-Ag-1/ GM-Tg-cynog-T51499-Ag-2 Cynomolgus/Rhesus macaque GM2A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T51499-Ag-1/ GM-Tg-felg-T51499-Ag-2 Feline GM2A protein Feline
GM-Tg-cang-T51499-Ag-1/ GM-Tg-cang-T51499-Ag-2 Canine GM2A protein Canine
GM-Tg-bovg-T51499-Ag-1/ GM-Tg-bovg-T51499-Ag-2 Bovine GM2A protein Bovine
GM-Tg-equg-T51499-Ag-1/ GM-Tg-equg-T51499-Ag-2 Equine GM2A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T51499-Ag-1/ GM-Tg-hg-T51499-Ag-2; GM-Tg-rg-T51499-Ag-1/ GM-Tg-rg-T51499-Ag-2;
GM-Tg-mg-T51499-Ag-1/ GM-Tg-mg-T51499-Ag-2; GM-Tg-cynog-T51499-Ag-1/ GM-Tg-cynog-T51499-Ag-2;
GM-Tg-felg-T51499-Ag-1/ GM-Tg-felg-T51499-Ag-2; GM-Tg-cang-T51499-Ag-1/ GM-Tg-cang-T51499-Ag-2;
GM-Tg-bovg-T51499-Ag-1/ GM-Tg-bovg-T51499-Ag-2; GM-Tg-equg-T51499-Ag-1/ GM-Tg-equg-T51499-Ag-2
Products Name GM2A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GM2A
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GM2A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.